Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09150 Ibrutinib GSE70138 HA1E Human 24h 0.12uM EID0035
Types Number Response transcription factors
Up-regulation 38 NR3C1; CHD4; GLI2; CTBP1; GTF3A; AHR; ILF2; GFI1; MYBL1; NCOA4; ZNF512B; BNC2; DLX2; TRIP6; NCOR2; LITAF; HMGN3; KLF5; ZNF22; NKX2-1; NFIC; MTF2; TCEA1; WWTR1; HIC2; YBX3; TSC22D2; GATA6; EN1; FOXF2; BMI1; NANOG; HOXD1; ZBTB38; ID1; TOX; BHLHE41; TOX3
Down-regulation 23 CNOT6; EGR1; PSPC1; ZNF189; NFE2; CREB1; MYB; BTG1; IKBKAP; PURA; SAP30; PTTG1; HHEX; CITED2; FOXC1; HOXB6; ZBTB16; LEF1; HOXB7; ERBB4; MEIS1; KDM5D; ZNF274