Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09116 Bosutinib GSE70138 HA1E Human 24h 10uM EID0035
Types Number Response transcription factors
Up-regulation 94 HMGN3; IRF9; IRF7; SP100; TRIM22; PHIP; TAF9B; PRPF6; GTF3A; CLOCK; MED17; SATB1; HES1; GLI3; ZNF264; RUNX1; ZNF24; HOXD1; KDM5C; FOS; RAD21; NFKBIA; JUND; CALCOCO1; INSR; PBXIP1; TCEA2; E2F5; TCF7L1; JUP; TRIM24; CEBPD; HMBOX1; VPS72; SOX15; SALL2; TFAP2A; ZNF165; AEBP1; NFATC4; MDM2; SIX3; ISL1; NFKB2; MEIS2; PRRX1; CREM; TCF21; SMAD1; RNF141; ERBB4; CDIP1; TRIB3; NR2F6; HIC2; CBFA2T3; ID1; CITED2; ZNF415; CCNH; SP110; ID4; EPAS1; RUNX3; ZNF623; PFDN5; ATF5; HLX; SPIB; HIPK2; TP63; ZNF467; ZNF665; IRF6; ETV5; ELF3; FOXF2; STAT3; ZHX2; TRPS1; FOXF1; ATF3; FOXG1; MYBL1; ZNF117; STAT1; IFI16; TOB1; ZNF423; NEUROD1; GATA6; BCL11A; SOX9; ST18
Down-regulation 67 TLE1; BASP1; PAX8; SOX4; DNMT3B; ABL1; DR1; ENO1; TBL1XR1; ZMYND8; SMARCA4; ELF1; MAF; DEK; FHL2; JARID2; ARID4A; SALL1; SMARCA2; HMGA2; RNF10; ZEB2; RBBP4; HMGA1; CRY1; ARID4B; VEZF1; FOXJ3; NR3C2; VGLL4; ATF1; FLNA; IRF4; ZBTB38; EGR2; FOSL2; MYCN; HNRNPD; PCGF2; NR2F2; PRKDC; DMTF1; RBM14; HLTF; ZMYM2; EDF1; HOXA10; MYCBP; SATB2; IKBKAP; ERBB2; CBFB; SAP30; SMAD3; TOX3; EGR3; NR1D2; SIAH2; ETS1; PDLIM1; NFIB; MAFB; BMI1; MAGED1; MTA1; ZNF274; HOXC6