Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09108 Cgp-60474 GSE70138 HA1E Human 24h 0.12uM EID0035
Types Number Response transcription factors
Up-regulation 431 EGR1; SOX17; NR1I2; TLX1; L3MBTL1; ZNF264; ZNF667; REL; TGFB1; KAT2B; HMGA1; CARF; ZBTB7B; CEBPA; ZSCAN31; E2F2; ZNF224; ZNF551; MZF1; HOXA3; EHMT2; ZNF556; TBX6; MDM2; NR4A2; MBD4; EGR4; HIF3A; HOXB3; DCC; POU3F2; CIITA; ESR1; ZNF358; CERS6; ZFP30; AR; ZFHX2; ZNF345; HAND1; TSHZ2; ZNF331; NEUROD4; DACH1; RING1; ZNF562; ZNF816; HMGXB3; ZBTB48; FOXF1; WDR77; HNF4A; DLX2; SP100; ZNF175; CALR; ZNF611; BAZ2A; TAF1; ATF7; CD3D; ZNF671; ZNF426; ZNF814; NR5A2; HOXB5; ESR2; SCAI; PDX1; ZNF107; RFX1; CNOT3; PGR; MED25; EVX1; SIX5; MYF5; ING4; ZNF76; FOXO4; ZNF665; RSF1; ETV1; ZNF536; SSBP3; HNF4G; VSX1; MAK; PBX2; NEUROG1; FOXJ1; IKZF4; SPI1; IKZF1; ZNF646; TAF6L; NKX2-5; GBX1; RORC; TONSL; HMX1; MYT1; THAP10; SOX3; CDX1; NR2E1; HNF1A; ZNF493; THRA; ZKSCAN1; ZEB1; SKI; ZNF205; ZNF44; MEIS2; CALCOCO1; MXD4; ZNF587; DLX6; ZNF215; HAND2; LZTR1; ASCL3; ZNF771; ZNF154; RBPJL; HEYL; ZNF254; ASH1L; TBX10; IRF3; NR6A1; PROP1; ZKSCAN8; GLI1; ERBB4; SRCAP; MEF2C; ZNF362; ATF2; ZNF136; FOXP3; ELK4; MAML3; KDM5C; HSF4; HOXC5; SALL2; PAX1; ZFPM2; NR0B2; SUPT7L; ZNF813; MNX1; ATN1; TRIM25; SSX7; SIX3; ZSCAN2; CDX2; ZNF117; ESRRB; RFX2; TFDP2; THRB; SIX6; ZBTB44; ZKSCAN4; ONECUT2; CREM; PRDM1; ZBTB20; NHLH1; ZIC3; ZNF235; TFAP2A; FOS; ZNF768; ZNF606; CRX; AFF3; HOXD3; BCL11A; TCF15; FOXH1; ZNF787; NKX2-2; TUB; ZNF415; CBL; HDAC5; ZNF721; NR1I3; ONECUT1; NR4A1; HOXC13; TULP1; PRDM9; TCEA2; FEV; E2F5; ARID3A; RFX3; SHOX; NKX6-1; MEIS1; NHLH2; MECP2; LDB1; ACTL6B; ZNF442; ZNF124; PAX3; KLF15; ATOH1; ZNF580; ZNF682; ZFP2; CEBPE; ZNF701; GFI1; SRY; ZNF711; FOXE3; ZNF75D; ZNF652; NR5A1; GATA6; TFDP3; SUPT6H; ALX4; NPAS1; MLXIPL; ZNF180; GLI3; ZNF529; NFAT5; HEY1; POU3F4; NEUROD2; ZNF695; ZNF112; ZNF407; E2F4; ZNF623; ZNF710; IKZF2; ZNF253; FOXD3; MXI1; POU2F3; ZNF287; IRF1; ZNF440; NFIX; NFKB2; ZNF749; ETV3; RBL2; ZNF391; ZNF544; ZKSCAN3; FEZF2; CDX4; ZNF573; KAT2A; ZNF654; SOX2; TCF21; FOXF2; ZNF550; HESX1; ZNF688; MAP3K10; FOXA2; CEBPD; ISL1; HLX; ARL2BP; NR4A3; PRMT2; KLF7; PAX7; ZNF225; NEUROD6; GSC2; HOXD1; MECOM; ZNF467; BRWD1; VENTX; HEY2; SOX5; CHD2; ZNF214; MYCL; SP140L; INSR; MLLT10; PRDM12; SOX18; HOXC8; ZNF43; CUX2; ZFHX4; ZNF80; LITAF; HOXB1; ZNF22; LIN28A; ZNF257; ZNF500; ZNF350; ZNF250; NEUROG2; NFIC; FOSB; ZNF85; VPS72; POU6F2; PHOX2B; BAZ2B; TAF1C; GLI2; ZNF33B; CBX2; POU5F1B; PFDN5; ZNF160; ZNF304; ARID5A; NKX2-1; PAX6; TBX5; ZNF835; IRF8; ZNF165; MYCN; NKX3-2; TEF; TCEB2; PEX2; HMBOX1; ZNF239; MSX1; ZNF778; CREBL2; CBX4; ZNF184; DMTF1; SOHLH2; CTNNB1; AES; PRDM14; SMAD5; INSM1; SOX21; ZNF91; DLX5; HIPK2; NR1H3; SLC2A4RG; NEUROD1; EMX1; GBX2; ZSCAN18; ZNF211; SCRT1; CHD9; CBFA2T3; PITX3; TCF7; PHF1; SNAI2; IRF6; MED14; HOXB13; TWIST1; KLF1; OLIG2; TRIM24; BNC2; IRF9; NRIP1; CRYM; WNT4; ZNF557; MYRF; CDIP1; EHF; MYCBP; TBX21; LHX3; MAZ; OVOL2; VGLL1; TAL1; STAT4; NR0B1; TDP2; KLF13; GATA2; GATA1; ELF3; HDAC9; NFE2L3; BARX1; ID1; EGR2; EPAS1; ZNF589; KAT6B; HIRA; NFATC4; GRHL2; HOXB6; ATF3; TCEA1; PRDM2; STAT3; ZIC1; RFX5; NR2F1; EGR3; PEG3; ETS1; TRPS1; HOXB2; ZNF423; ST18; STAT1
Down-regulation 192 CCNA2; FOSL1; ABL1; FHL2; XBP1; UBE2I; CDK7; PAX8; TLE1; NUP62; RBPJ; PUF60; NFKBIA; CTCF; HNRNPD; CRK; BRD3; SMARCA5; NCOA6; MBD2; CENPF; ZFP36L1; NFIL3; ING2; FOXO3; DR1; RARA; EED; USP22; RBBP4; SAFB; EZH2; BAZ1B; HDAC2; SMARCE1; SMAD2; PIAS2; APEX1; SOX4; TRIM29; MED27; BASP1; RBM14; TAF5; RNF138; KAT5; KLF4; MYC; SAP30; AATF; DNAJC2; SAFB2; SIX1; RNF111; BTG1; HOXA10; ITGB3BP; ZNF410; RAN; SNW1; ZBTB24; SETD2; KAT6A; HOXC10; BRCA1; KAT8; CCDC59; CIZ1; NFYB; RNF4; CRY1; NELFB; TEAD4; DEK; DPF2; NFKB1; MED6; ADNP; BACH1; MNT; TSC22D2; ADNP2; BAZ1A; SF1; FOXO1; HOXA5; KDM2A; NR2F2; RELA; KAT7; ZMYM2; RNF6; ERBB2; BCLAF1; PATZ1; ELF5; FOXK2; TLE4; SMARCC1; TBL1XR1; ECD; SMAD7; VEZF1; MED24; POLR2A; TRIM32; GTF2IRD1; ARNTL; ZNF266; NRBF2; HMGB1; CBX5; ZBTB11; GATAD2A; NCOR2; KLF10; PCGF2; BIRC2; SCAND1; NKX3-1; LIMD1; SAP130; HOXA11; RXRA; RBPMS; BLM; BHLHE40; PHF2; CBX3; TRIM16; TULP4; FOSL2; KLF11; HMGB2; MLXIP; MAFB; TBPL1; HOXC6; REST; ELF1; CHD1; IRF2; IKBKAP; IRF4; KDM5D; TCF7L1; AFF1; SERTAD2; ID2; TBL1X; TTF1; MED1; TBP; ATF1; SIX2; FOXC1; TGFB1I1; HSF2; RREB1; JARID2; ZBTB1; SOX9; LMCD1; PHF20; NR1H2; HTATIP2; YBX3; POU2AF1; CTBP2; KLF2; ZNF226; MAF; FOXD1; FOXJ3; HOXB7; TFAP2C; SUV39H1; SUB1; CBFB; ZFP36L2; MAGED1; ZNF217; PBX3; ID4; ERG; WWTR1; PTTG1; TOB1; PAX5; TP53; BMI1; CREB1