Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09107 Cgp-60474 GSE70138 HA1E Human 24h 0.37uM EID0035
Types Number Response transcription factors
Up-regulation 537 EGR1; L3MBTL1; NR1I2; REL; CARF; ZNF224; ZNF264; ZNF107; ZNF667; MDM2; ZBTB7B; MBD4; NR4A2; RBL2; ZNF551; TLX1; DACH1; KAT2A; ZNF331; RING1; ZNF426; EVX1; HOXA3; ZNF345; TLX2; ZNF562; ZNF556; RFX1; TAF1; ASH1L; WDR77; ZNF136; ZNF205; TAF6L; ZNF165; FOXF1; SKI; TBX6; EHMT2; HNF4G; HSF4; ZNF358; CERS6; IRF3; ZNF816; HMX1; ZSCAN31; ZNF671; NR4A1; TFEB; TGFB1; ZNF611; PBX2; ZNF362; TSHZ2; NKX2-5; SOX17; HAND2; ZNF254; MTA2; GBX1; HOXB3; ZNF665; SCAI; NEUROD4; ATF7; HOXB5; NR4A3; BCL11A; RSF1; ZNF44; PAX1; ZNF771; TUB; ZKSCAN8; PDX1; BRWD1; ZNF175; HEYL; SRCAP; PRDM8; EGR4; ESR2; FOXL1; PHF1; SIX5; ZNF117; POU2F2; ZNF253; MXD4; ZNF814; HNF1A; TBX10; ZNF135; MAML3; MEIS1; FOXH1; RFXAP; RBPJL; ATF6B; IKZF1; ZNF652; SUPT7L; ZNF493; SPI1; ZNF33B; SOX3; NR6A1; TULP1; IRF8; THRB; ZNF268; ZNF91; CDX1; POU3F3; HESX1; E2F5; ING4; CIITA; PGR; NFKB2; TONSL; PRDM1; ZFHX2; ZNF813; IKZF4; PRMT2; ZNF391; RORC; MEF2C; ZNF154; LITAF; HDAC5; ZNF43; MED25; FOXP3; VSX1; ZNF768; ZNF180; HIF3A; TCEA2; ERBB4; ZIC3; E2F1; MYF5; IFNB1; HNF4A; KLF15; AFF3; LMX1B; VPS72; HOXC5; RAX; ARID3A; ZNF573; LHX5; TAF9B; MYCN; NEUROG1; MAP3K10; HAND1; CDX2; ETV3; ZSCAN18; CREM; TCF15; THAP10; ZNF141; FEV; CRTC1; HLX; MAFK; ZNF124; SKIL; KDM5C; CRX; RNF2; ZKSCAN4; ZBTB44; AFF4; RFX3; GRIP1; NR5A1; SOX21; SRY; NPAS1; TBL1Y; ATOH1; HNF1B; PHOX2A; MED14; POU3F2; NR2E1; ZNF211; DLX6; CNOT3; ZNF75D; CBL; MAK; ZNF701; ZNF749; ZNF529; RFX2; HOXB8; ZNF787; ESRRB; ALX4; RUNX2; LZTR1; ZSCAN2; SALL2; ZNF695; CUX2; ZNF350; DCC; SSBP3; ZNF711; PPARG; ZNF675; NRL; OVOL1; KAT2B; ZNF8; FOXO4; ZNF550; TBX1; ZNF696; ZNF549; SSX7; MYT1; ONECUT2; ZNF682; NFIX; LIN28A; NHLH2; FEZF2; NHLH1; SIX3; ZBED2; ZKSCAN1; NR0B2; PRDM9; SREBF2; ASCL3; ZNF225; ZNF407; ZNF613; TAF1A; ZNF219; NEUROD2; PROP1; HOXB1; ZNF536; ZNF235; HOXA6; ZNF304; EMX1; ZNF276; ZNF287; CDX4; WWP1; PHIP; GSC2; MLXIPL; HES1; MLLT1; ZNF83; THRA; ZNF440; E2F4; NFATC3; GATA6; ESR1; CEBPD; HEY2; DOT1L; NEUROG2; HOXC8; TCFL5; NFE2; ZNF215; SUPT3H; ZNF442; ZNF770; ZNF606; FOXD3; PRDM14; ZNF112; ZNF415; NKX6-1; ZNF257; TEF; POU5F1B; E2F2; FHL5; CAMTA2; CAMTA1; MAPK8IP1; FOXJ1; ZNF710; ETV7; ACTL6B; ZNF471; SOHLH2; SOX18; MLLT10; ZNF81; ZNF221; FOXF2; ISL1; KLF13; ZNF571; ELK4; CD3D; ZNF41; ZNF669; MXI1; SOX5; EPAS1; ZBTB7C; ETV2; ETV4; ZNF654; SIX6; MECP2; SCRT1; OLIG2; CBX2; ZNF721; SOX2; GTF2I; TFDP3; LHX3; POU2F3; FOXN1; KLF8; AR; ZNF273; ZNF480; ZSCAN16; PITX3; ZNF646; WHSC1L1; BARX2; VENTX; TAF4B; ZKSCAN3; GFI1; NKX2-2; EZH1; WNT4; ZNF35; DLX2; PPARD; ARL2BP; PAX7; PBXIP1; ZNF586; ASCL2; ID1; TBX5; THAP9; TCF21; NFE2L3; ONECUT1; RARG; ZFHX4; CALCOCO1; IKZF3; HIC1; NEUROG3; APBB1; NR5A2; LMO1; INSM1; ZNF780B; ZNF93; TLX3; TBX2; PEX2; POU6F2; POU3F4; ZNF214; ZNF688; ZNF623; VGLL1; TCEB2; NKX2-1; FOXE3; FOS; ZNF778; TULP3; ZBTB20; CHD2; PHOX2B; IRX5; GLI1; ZNF80; FOSB; ZFP2; IRF6; HMBOX1; CDIP1; PRDM5; DYRK1B; CBFA2T3; FOXB1; MEIS2; ZNF500; HOXC13; TEAD3; ALX3; ZFP69B; BARX1; FOXA2; ESRRG; AIRE; CEBPE; HOXD12; ZNF184; TAF1C; HDAC11; ZNF467; ZNF223; LDB1; SOX14; VHL; TDP2; DLX5; ZNF557; ZNF22; PRRX1; SP4; POU4F3; ZNF174; ZBTB3; ZNF329; PPARA; ZNF10; YEATS4; ZNF250; CREBL2; HOXD3; PAXBP1; ZNF468; PAWR; ZBTB43; ID4; TWIST1; UTF1; POU1F1; ZNF79; PAX6; PRDM12; HOXD13; GATA1; ARID3B; SLC2A4RG; ZNF160; TP73; YAP1; FOXI1; NFATC4; ETS2; ZNF85; GATA2; TFDP2; NEUROD6; ATN1; TFEC; ZNF544; KLF1; GBX2; CALR; NR1I3; HOXD1; GLI2; TRPS1; PROX1; HEY1; DMTF1; HOXB13; NANOG; TBX21; HIRA; TCF4; FUBP1; NFAT5; ZEB1; HIPK2; MDM4; CCNH; DLX4; NR1H3; CREB3L2; STAT4; GRHL2; HDAC9; NEUROD1; SOX13; EYA1; SMAD5; CREG1; ATF3; IRF9; ZSCAN9; MYCL; TFAP2A; MECOM; MED12; MYRF; NFIC; KLF7; EHF; NR2F1; NR0B1; NR2F6; MYBL1; ZNF589; ZFPM2; TCEA1; LYL1; TRIB3; EGR2; SPDEF; MYCBP; CRYM; EMX2; HOXB2; PRDM2; ID3; SNAI2; ZBTB16; ST18; ZIC1; ETS1; SSBP2
Down-regulation 197 FOSL1; CCNA2; FHL2; ABL1; UBE2I; TLE1; XBP1; NUP62; PAX8; PUF60; NFKBIA; ZFP36L1; MYC; BASP1; SMAD2; SMARCE1; BTG1; CRK; HNRNPD; BAZ1B; TCF12; DDIT3; MBD2; EZH2; ITGB3BP; ATF4; CTCF; HDAC2; CENPF; SMARCD3; BRD3; CDK7; NONO; USP22; RBBP4; KLF10; SMARCA5; RNF138; NCOA6; ZNF410; BHLHE40; RARA; PIAS2; NFIL3; NFYC; ING2; FOXO3; RAN; SAP30; SETD2; HOXC10; RERE; RBM14; NKX3-1; NCOA4; AATF; RBPJ; ATF1; PATZ1; TBL1X; TBPL1; JARID2; KAT8; SCAND1; ECD; BCL10; POLR2A; ZMIZ2; HOXA10; CCDC59; APEX1; BAZ1A; ZBTB24; KDM2A; RELA; HOXB7; DR1; ZNF146; VEZF1; MED6; KAT5; TRIM32; BIRC2; KAT7; NR2F2; DNAJC2; PHF20; POU2AF1; SF1; SOX4; UBE2B; TGFB1I1; TRIM28; PLAGL2; GTF2A2; MAX; TBP; SNW1; RNF6; ZMYM2; CEBPG; HMGB2; KDM5D; IRF2; ARNTL; ZBTB11; BRCA1; MNT; CRY1; FOXO1; GTF2IRD1; SMAD7; REST; MEF2A; SP3; SIX1; DDX17; NPM1; POU4F1; PCGF2; MED1; FOXJ3; IRF4; KLF4; TSC22D2; NFKB1; KLF2; HMGB1; RREB1; SMARCC1; BRPF1; ADNP2; BCLAF1; SIX2; ELF1; TRIM16; SFPQ; TBL1XR1; HOXA11; TEAD4; PTTG1; CBX3; DPF2; MTDH; BRD8; NCOR2; MED24; MAFB; FOXD1; CBX5; CTBP1; RLF; AFF1; ELF5; RBBP7; TFAP2C; MLX; CHD1; FOXM1; NELFB; ID2; NRBF2; SMAD1; DEK; HOXC6; NRIP1; DDX5; MAGED1; RXRA; LMCD1; CBFB; CARM1; SERTAD2; SUB1; TP53; CEBPB; CREB3L1; HSF2; VGLL4; NFIB; TCERG1; JUND; EDF1; FOSL2; TAF10; IKBKAP; YWHAB; SUV39H1; CTR9; ERBB2; SSX1; ZBTB18; TRIM29; MTA1; BMI1; SOX9; FOXC1