Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID09063	Idelalisib	GSE70138	HA1E	Human	24h	1.11uM	EID0034

Response Information :

Types	Number	Response transcription factors
Up-regulation	98	GATA3; VGLL4; RELB; KDM5A; RHOA; TRIM16; TRIM32; SMARCD2; PARP1; SMARCC1; TXNIP; MTA1; SUV39H1; TOPORS; ARID4B; BCL3; MEN1; IRX5; ADRB2; HMGA2; CEBPA; PPARG; ASXL1; HMG20B; ARID4A; TSC22D3; SSX1; NFX1; MYBL1; MED24; ZNF552; PAX5; TCF7; EP400; PIAS3; NCOR2; ADNP; TWIST1; SP110; TRIM22; PTTG1; NCOA6; NR1H3; TTF1; MITF; FLNA; CEBPB; DLX5; ZBTB38; HSF2; RUVBL2; SOX9; MAGED1; TBX3; LITAF; NR4A3; CREM; KAT7; ZFP36L2; MSX1; TFCP2; ELF1; HTATIP2; KLF10; CUX1; FOXC1; NR4A1; BHLHE41; ZNF226; ERBB2; PUF60; FOXA2; SPIB; YBX1; HOXA10; POU2AF1; ZEB1; ID2; LMCD1; CREG1; ECD; MKL2; KDM5D; ZBTB18; MYCBP; NR2F2; ZNF652; SUB1; NKX2-1; PIR; STAT6; EGR1; SPDEF; IRF4; EGR3; ELF3; HOXB7; BASP1
Down-regulation	130	THAP11; ACTL6A; ZFP36L1; CNBP; ZNF148; BRD4; ZNF12; RNF138; LHX1; CDK9; GMEB1; ZBTB48; ZZZ3; MXI1; BRD2; TCEA1; CIZ1; KLF1; ARNT; CBFA2T2; ZIC1; CTBP2; GMNN; ZNF177; ZNF24; SMARCA4; TULP3; ZNF410; MYCL; POU3F2; NFATC4; ZSCAN16; ZNF562; MSC; E2F3; CCNC; CCNA2; COPS2; TCF21; HIPK1; HDAC7; TFAM; MAX; EHF; IRF3; RFXANK; EWSR1; PRDM12; SUPT3H; LDB1; SUMO1; KLF5; GFI1B; IRF1; CEBPE; ZNF573; SOX4; ZNF175; ZNF623; ZNF606; DEK; PRRX2; ERG; ZSCAN9; INSM1; OLIG2; MEOX1; ZNF688; LYL1; SMAD1; JUND; MTF2; ZNF232; GATA1; ZNF266; ASCL1; ZNF3; HLX; MECP2; ZNF189; HOXB13; TSC22D4; CITED2; HEY2; ZNF146; SMAD4; TAL1; GLI2; TOX; FOXL2; NFKB2; ZNF140; SIX1; TCF7L2; FLI1; ZBTB43; ATF5; HIPK3; PBX3; NFIB; BAZ2B; MYB; PAX6; HDAC9; ING3; ATF3; TGIF2; RBBP8; SATB2; STAT1; MAF; NFE2; BARX1; AEBP1; ZNF91; CREB1; MAFB; SNAI2; DAXX; PEG3; HOXD1; HMBOX1; PITX2; PPARD; SOX11; EMX2; ZSCAN18; WWTR1; ID4; TOX3