Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID09062	Idelalisib	GSE70138	HA1E	Human	24h	3.33uM	EID0034

Response Information :

Types	Number	Response transcription factors
Up-regulation	187	ETV1; CTR9; MXD4; HDAC6; PPARG; HMGA2; KDM5A; NR1H3; PHF8; SUV39H1; PARP1; MEN1; SFMBT1; RBM14; SSX1; STAT2; RHOA; NFX1; PLAGL1; BAZ1B; TFCP2; NR2F1; LIMD1; KAT5; TRIM28; RUNX3; ARID4A; NFYC; FOXO4; PITX1; HOXC6; MITF; TOX; RELB; POU2AF1; KDM5D; SMAD6; GABPB1; DDX54; SETD2; MNX1; CEBPA; FOXA1; ELF1; SND1; BCL3; TRRAP; IRF2; HCFC1; NPAS2; HMG20B; ALX1; BAZ1A; SP140; KAT6A; ELK1; ZSCAN31; SMAD2; TRIM32; ZNF286A; ESRRA; PTTG1; HHEX; NR2F2; BCOR; HMGA1; KAT7; POLR2A; NONO; RFX5; FOXC1; ZNF226; SKI; SOX10; ZNF552; CRK; ELF3; YAF2; TCF20; HOXC10; ADNP; ZNF329; SMARCA5; RBL1; HOXC4; PUF60; FOXD1; TOPORS; KAT6B; MAGED1; STAT3; MEOX2; BHLHE40; DNAJC2; WT1; MED24; BPTF; PCGF2; EZH2; RUVBL2; TOB1; MTA1; CUX1; NR4A1; NR0B1; YBX1; RBBP4; ENO1; AFF1; KMT5A; IL16; PDLIM1; EGR2; THAP1; MYB; BRD8; MDM4; PPARGC1A; TP63; ZNF711; REPIN1; DRAP1; AATF; PIR; KLF2; JUP; STAT4; SP110; ZBED2; ID2; MYCBP; STAT6; IRF4; MBD2; CBX5; CBX6; ZNF580; SERTAD2; NCOA6; BRCA1; HMGN3; SP2; TBL1XR1; SPEN; SAP30; NFAT5; CNOT3; ATF7IP; RERE; CREB3L1; EGR1; DMTF1; ECD; TBX2; TCF7; IRF8; SFPQ; SMARCA1; SCAND1; TAF10; HMGB3; TRIP6; TSC22D1; HOXA11; SIAH2; TRIM22; NFIB; FHL2; TWIST1; HLF; POU4F1; EMX2; TXNIP; EGR3; PEG3; TGIF1; CRYM; CITED1; ZFPM2; HOXB6; HOXB7; TOX3; CALR; RBPMS; NKX3-1; BASP1; NR3C1
Down-regulation	227	THAP11; ZFP36L1; CNBP; ZNF410; BRD7; ZNF12; LOXL2; TCEA1; HIPK1; ENY2; FOXN3; TULP3; ZNF93; RAD21; TCEA2; SUMO1; ZNF32; E2F3; EWSR1; ZNF573; GTF3A; CREB5; PMS1; FUBP1; GMEB1; ZNF16; CEBPG; NR2E1; COPS5; ZNF768; CCNC; NFE2L1; ZNF232; ARNTL2; GMEB2; BCL10; ZNF91; SUPT3H; BRIP1; ZNF423; ZFP36L2; ESRRB; ZBTB18; ZNF217; KLF7; ZNF354A; DEK; HOXB13; CHD8; PSMC3; ZNF7; EED; RXRG; HINFP; PAX6; GBX2; BTAF1; TAF9B; PNRC1; ILF2; GMNN; TEAD4; NR2C1; MSC; CBX2; PEX2; GLI3; SCMH1; ZNF443; ZSCAN2; ZSCAN9; ACTL6A; ZBTB7B; MDM2; TAF11; CDX4; MED17; MXI1; ZNF302; CSDE1; ZNF430; MAFK; NFATC4; POU3F2; SRCAP; PKNOX2; HOXD12; SPI1; RNF6; HMBOX1; KAT8; HIRA; HOXB1; THAP4; ATF3; TBX10; POU5F1B; NFYB; HOXD3; ALX3; MAPK8IP1; PATZ1; BBX; ZNF177; PCGF3; CEBPE; PIAS1; NPAS1; ZMIZ1; ZNF415; OVOL2; ARID5B; ALX4; SOHLH2; HAND2; TRIP4; FOXH1; HMGB1; ZNF688; SOX3; TRIP11; VPS72; YWHAB; ZNF83; MYF6; HOXC8; TCF21; ZNF281; KLF1; MAP3K10; ZNF140; ACTL6B; ZNF250; MED13; PRDM12; ZNF667; ZNF665; TP73; CDIP1; TAF5L; ZNF24; PROP1; NFIC; CCNH; WHSC1; INSM1; OLIG2; HLX; ZNF22; NR5A1; NR2F6; CBFA2T2; RUNX1; RLF; NANOG; NFKB2; ZNF85; LIN28A; RBPJ; KAT2B; GLI2; PRRX2; ZNF467; ZNF623; ZNF426; SMAD1; ATF4; TDP2; DLX2; ERG; ZEB1; FOXO1; AIRE; PRDM14; TAF7; CDYL; GFI1B; ZNF589; ELK3; BRD4; KLF11; PAXBP1; MTF2; ZNF606; ZIC1; TGIF2; AEBP1; TBX3; MEIS2; INSR; ESR1; ATF5; IRX4; MED25; MEIS1; TAL1; GATA6; RORA; ABL1; PBX3; CUX2; ZSCAN18; ZBTB16; ZNF266; ZNF160; BMI1; YAP1; NEUROD1; TRPS1; PITX2; PRKDC; ZNF44; CREB1; ZNF331; CHD9; HES1; ST18; BCL11A; MYCN; FOSL2; FOXG1; ZMYM2; ZNF117; HTATIP2; MAF; PPARD; ZNF274