Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09041 Osimertinib GSE70138 HA1E Human 24h 0.12uM EID0034
Types Number Response transcription factors
Up-regulation 53 TOX; MTA2; ZNF329; ZIC1; YEATS4; EYA2; SOX5; TOPORS; SOX17; FOXJ1; ZNF165; CTNNB1; MDM4; SMARCB1; HEY2; NKX2-2; SMARCA1; TULP4; SOX15; SOX13; BBX; FOXA2; HLX; TRPS1; TCF7L1; ST18; ZNF432; NR1D2; OSR2; ZNF131; CREB1; ATF3; NR0B1; MED14; HMGB3; ZBED2; MEOX2; MSX1; HDAC9; IRF6; FOXF2; PROX1; ZSCAN18; ZNF589; ERBB4; ZNF423; WT1; LITAF; STAT1; ZNF331; ESR1; SPDEF; PPARD
Down-regulation 33 SOX9; FOXO3; MTDH; GTF2I; MNDA; NFE2L3; BMI1; ZNF267; XBP1; RUNX3; DNAJC1; EYA1; EGR3; CCNC; NCOA4; ZNF146; BASP1; AFF1; CTBP1; KLF2; IRF8; FLNA; IFI16; NR2F2; HOXC6; ZEB2; HTATIP2; RFX5; GATA6; BHLHE41; LEF1; CREG1; PBX3