Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID09040	Osimertinib	GSE70138	HA1E	Human	24h	0.37uM	EID0034

Response Information :

Types	Number	Response transcription factors
Up-regulation	38	TBX2; DMTF1; BIRC2; SOX9; BCL6; NR1D2; SAP30; WWC1; ERBB2; MYCBP; CBX3; ELF5; USP22; EZH2; NFKBIA; AHR; NR1H2; MXI1; SIX1; HOXB2; ZBTB18; RFX5; FLNA; BHLHE41; NR2F1; HMGN3; BTG1; NR2F2; CEBPB; LMCD1; TSC22D1; MECOM; MNDA; EGR3; ID3; NKX3-1; EGR2; BASP1
Down-regulation	79	RORA; JUP; IRX4; TULP4; SLC2A4RG; FOXL2; EP300; CDK8; TERF1; PSPC1; TRIM24; CNOT3; OVOL2; ZNF623; ASCL1; NHLH1; HMBOX1; MKL2; ATF5; HHEX; SRCAP; IRF6; PITX2; CBFA2T3; KDM5C; PRDM2; CERS6; PBXIP1; BCL11A; NEUROD1; MLXIP; ESR1; GATA4; ZBED1; SSBP3; GATA6; MYB; TCF21; TAL1; NFE2L2; STAT4; ZFP36L2; ZMIZ1; CALR; ZBED2; BNC2; IRF7; CUX1; ATF3; ZNF264; TCF4; ARID3A; FOXA2; INSM1; SPIB; TRPS1; PROX1; ELF3; NFATC4; TFAP2C; HES1; MYRF; SMAD1; ST18; LITAF; NKX2-2; RUNX3; CREB3L2; GLI2; NFAT5; ZNF160; FOXG1; NFE2; REL; ZNF117; HOXD1; PPARD; TCFL5; PEG3