Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID09037	Osimertinib	GSE70138	HA1E	Human	24h	10uM	EID0034

Response Information :

Types	Number	Response transcription factors
Up-regulation	56	DDIT3; NR1H2; KLF11; HMGA2; FOXO4; FOXN3; TXNIP; HOXA5; CBX7; HBP1; BTG1; TCF20; VGLL4; CALCOCO1; SREBF2; NFYB; OSR2; IRF9; SOX9; PBXIP1; TSC22D3; TRIM16; AFF1; FOXC1; ATF4; KAT6A; MITF; STAT1; NR1H3; NR1D2; INSR; MTF2; ZNF91; HDAC9; ZNF165; ERBB2; HOXB6; IRF1; ZFP36L2; IRF6; ZEB1; RBBP8; MECOM; MXI1; CREG1; HEY1; CEBPB; FOXG1; IFI16; RFX5; ZNF589; BHLHE41; HOXB7; PPARD; PBX3; NKX3-1
Down-regulation	67	CCNA2; GABPB1; XBP1; MYBL2; SMARCC1; C1QBP; WT1; GTF3A; PLAGL1; MTDH; RB1; PREB; TAF4; TCF21; RARA; RNF14; GATAD2A; MAGED1; IRF4; PPRC1; SLC2A4RG; ADNP; FOXD1; TERF2; FOXM1; BAZ1A; KLF7; ILF2; BNC1; MYCN; RBM14; FOXL2; ZMYM2; SUB1; NCOR2; GFI1; BNC2; TGIF2; DNAJC2; YWHAB; CBFA2T3; MYB; NFE2; CBFB; SMAD3; HLF; ZNF652; ERG; CUX1; VDR; ZNF124; GLI2; PITX2; CREB3L2; POU2AF1; ZFPM2; KDM5D; BACH2; TCF4; HIRA; ZEB2; MYRF; SMAD7; EGR3; GTF2A2; SPDEF; PEG3