Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID08984	Ibrutinib	GSE70138	HA1E	Human	24h	3.33uM	EID0034

Response Information :

Types	Number	Response transcription factors
Up-regulation	78	TRIM22; STAT1; GATAD2A; IRF9; IKZF5; SP110; HLTF; USF2; CEBPG; NFKBIA; SUB1; BAZ1B; NUP62; TAF9B; TCF20; SOX9; TAF10; HNRNPD; WWC1; FLNA; MED21; RUVBL2; LEF1; SMAD4; IRF1; SMAD6; ZNF146; PTTG1; DPF2; SP100; SIAH2; BHLHE40; FOXA1; UBE2B; RBBP4; PIR; NFIB; ZNF302; CRY1; ZBTB38; HMG20B; EZH2; BATF3; RSF1; CTR9; RNF141; ADNP2; CITED1; STAT6; CCDC59; RFX5; MBD2; TSC22D1; ELF5; USP22; CTBP1; MSX1; TBL1X; IRF7; SIX2; TGIF1; HTATIP2; TBL1XR1; ID2; NR1H2; PIAS2; ID3; TRIP6; RBBP8; CEBPB; TRIM29; IFI16; BTG1; CREG1; LMCD1; ID4; HEY1; BASP1
Down-regulation	160	GRHL2; PSPC1; BRD7; RNF6; NANOG; APBB1; SNAPC4; CASZ1; EZH1; CDC5L; ZNF93; ZIM2; ZNF232; BNC2; ZNF281; ZNF573; IL16; CENPF; NR0B2; ETV6; FOXI1; HSF4; TAF5L; OVOL2; CAPN15; TERF1; ZNF692; MED20; ERG; ZNF701; GFI1; C1QBP; HMX1; PRDM2; AEBP1; CAMTA2; E4F1; GATA4; ZNF44; ZNF443; THRB; MYRF; HOXC4; CBX4; SMARCB1; CHD2; TAF9; PIAS1; RAD21; NHLH1; WT1; CBFA2T2; SNAI2; ZNF264; SOX21; HOXB5; ZNF85; PLAG1; FOXH1; ZNF394; NFATC4; MEIS1; LIN28A; NR1I3; ZMIZ1; PAXBP1; POU5F1B; CBX6; SSBP3; ZBED1; PRDM14; BARX1; OSR2; PAX5; ZKSCAN3; ZNF117; AIRE; EYA1; VPS72; TGIF2; ZNF557; HLX; ZNF423; MYCN; KLF13; LHX3; ZNF266; ZNF665; PROX1; ZNF124; PRRX1; ZNF611; ATF3; ZNF160; ARNTL2; ZNF589; CSDC2; ZNF721; ZNF217; CITED2; PAX6; HIPK2; FOXL2; NR4A2; ST18; NCOA3; ELF3; ZNF544; MAF; GTF3A; ZNF778; ZNF623; NCOA2; TCF21; VGLL1; SALL2; PRRX2; TGFB1; ZNF606; TOB1; ATF5; NEUROD1; CUX2; HOXD1; HES1; GLI2; YBX3; TCF7; RARG; ING2; ZBTB16; NFAT5; HMBOX1; EPAS1; HOXB2; HOXC10; ZIC3; TFAP2C; SMAD7; EGR2; ADRB2; HIRA; ZMYM2; DACH1; CALR; TXNIP; PEG3; SPDEF; GATA6; BACH2; ZNF91; TOX3; TCF4; EGR3; KLF4; BHLHE41; ERBB4; BCL11A; TCFL5; ESR1