Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08970 Pf-04217903 GSE70138 HA1E Human 24h 0.04uM EID0034
Types Number Response transcription factors
Up-regulation 81 VGLL4; RBBP4; RBBP5; FOXJ3; TCERG1; HSF2; PTTG1; DMTF1; NFKBIA; GATAD2A; HNRNPD; BTG1; NR1D2; SIX1; FLNA; ZBTB38; RFXANK; RUVBL2; HLTF; SETD2; BRD8; TRRAP; TBPL1; CBFB; WWC1; HTATIP2; ARID4B; BAZ1A; MBD2; BBX; SCAND1; BCLAF1; MED24; CDK9; NR1H2; ADNP2; EDF1; SHOX2; BMI1; MED1; TAF10; MAGED1; JARID2; SUB1; HMG20B; USP22; BCL3; SMAD2; PCGF2; PUF60; CSDE1; KAT7; CRY1; TAF7; NFIB; DAXX; KLF6; CHD1; PIAS2; ZNF274; HDAC1; CREB3L1; RFX5; FOXC1; TBL1XR1; FHL2; SATB2; IKBKAP; SOX9; STAT1; MSX1; PIR; NR2F2; CREG1; LMCD1; TSC22D1; KDM5D; HMGB2; AHR; MAFB; BASP1
Down-regulation 243 TRIB3; CCNA2; NANOG; ATF3; OVOL2; TP63; UTF1; HIC2; HIPK2; HOXB5; ARNT2; RAD21; TCEA1; FOXF1; HNF4A; EN1; ZNF440; ATN1; CASZ1; NR6A1; ESRRB; ZNF232; HOXC13; NRL; BNC1; NR2E1; RXRG; NR5A1; NR5A2; MNX1; ZIM2; ZNF74; TLX3; NR1I3; EZH1; ETV3; EP300; ONECUT1; CBFA2T3; ZNF557; FOXH1; VPS72; ZNF33B; ATOH1; TFDP3; FOXA1; CHD2; POU5F1B; CERS4; LIN28A; CHD8; CIR1; DLX4; LZTR1; HNF4G; NEUROG2; POU6F1; POLR3C; HOXB13; EMX1; CD3D; HOXC11; AIRE; SOX5; ERBB4; HOXB8; HOXD1; E2F4; SOX15; ZBTB44; DYRK1B; NCOA2; HOXD11; ZNF695; HOXC4; FOXA2; SCRT1; THRB; POU6F2; SNAPC4; CRYM; CDIP1; PRDM9; SRY; ZNF22; NCOA3; CCNH; PRDM5; CBX2; SIX6; GRHL2; ZFP36L2; MYRF; MAPK8IP1; ZBED1; MED15; TULP2; SOX13; NR0B2; ZNF701; GATA4; BNC2; ARID1A; ZNF214; PRDM14; KDM5C; NHLH1; PRRX1; ZNF573; FOXF2; HLX; ZNF669; PKNOX2; ZNF154; ZNF611; SSBP3; PRDM2; CRX; INSM1; ZNF44; NFATC4; FOXG1; PPRC1; NEUROD1; CBX4; YAP1; CAPN15; TP73; AR; NR1H3; SETDB1; MKL2; ESR1; TBX5; KLF13; ZNF165; SPDEF; NKX2-2; SOX3; CALR; ARID5B; NEUROD2; ARID3B; E4F1; ZNF467; OVOL1; KLF7; DLX5; PROX1; ZNF721; BRD4; ZIC1; ID1; SIX3; SSBP2; SOX21; IRX4; ZNF160; HMBOX1; FEZF2; TAF1C; ST18; ZIC3; ZBTB16; OSR2; ZEB1; GATA6; GATA1; MED17; TTF2; ZNF589; OLIG2; SALL2; ZNF235; INSR; HOXC8; ATF5; TOX; ARID3A; ZNF778; IRF6; ZNF654; ZNF665; SOX18; SOX17; ZNF623; CSDC2; NFIC; E2F8; PGR; TBX1; LHX3; TCF21; TFAP2A; ZNF500; ELF3; MEOX2; HOXB2; MEOX1; PITX2; MAP3K10; PRDM1; FOXO1; NFAT5; HOXB6; AEBP1; HOXC10; RARG; ZNF266; BARX1; LYL1; PAX6; CREM; HES1; SRCAP; NR2F6; HOXB7; MYBL1; ZNF117; DLX2; ZNF124; BCL11A; NKX2-1; HIRA; SNAI2; ZNF264; ZNF423; GLI2; TRPS1; TBX3; TGIF2; LITAF; ZNF415; MEIS2; NFE2; PEG3; EPAS1; MECOM; ZNF652; PPARD; NFKB2; SMAD7; TCFL5