Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08953 Bosutinib GSE70138 HA1E Human 24h 10uM EID0034
Types Number Response transcription factors
Up-regulation 55 TSC22D3; ID1; NRIP1; FOS; ATF3; MNAT1; STAT1; MECP2; BTG1; ZNF91; CEBPD; MDM2; BIRC2; NFKBIA; KLF11; CLOCK; PHIP; NR4A2; KLF10; JUP; ZNF331; CREM; ZNF423; IRF9; ZNF778; PAX6; IRF1; TDP2; TOB1; CITED2; TRPS1; NFAT5; ID3; JUNB; TCF21; ZNF131; PURA; ZNF415; NFATC4; PEG3; ZIC1; NKX2-2; SMARCA1; NEUROD1; INSM1; IRF6; ST18; MSX1; CREB1; ERBB4; MEIS2; TXNIP; ZSCAN18; SUZ12; EGR1
Down-regulation 58 SMARCC1; PAX8; TLE1; ZBED4; TGS1; PRKDC; NCOR2; TRRAP; SMARCA2; XBP1; VGLL4; ZNF217; CBFB; TBL1XR1; DNMT3B; ARID4B; ENO1; CREB3L1; FOXJ3; FHL2; AHR; HOXA10; MAZ; TFAP2C; ZMYM2; NCOA4; STAT6; KAT7; SHOX2; DNAJC2; BHLHE41; CBX3; GTF3A; MAF; HTATIP2; MAGED1; TBL1X; NFE2L3; SMAD3; ELK3; HDAC1; NR2F1; NR2F2; WT1; FOSL2; MYCN; EGR3; HOXC6; BASP1; ZEB2; NFIB; KDM5D; MECOM; SAP30; EGR2; ZBTB18; LEF1; ZNF274