Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08944 Cgp-60474 GSE70138 HA1E Human 24h 1.11uM EID0034
Types Number Response transcription factors
Up-regulation 549 NFKBIB; FOXF1; SOHLH2; STAT2; KLF9; NR4A2; PRDM13; ETV1; MYB; CD3D; MXI1; KDM4C; GATA2; ZNF331; OLIG2; FOXJ2; ZBTB44; JAK2; TRPS1; THRA; SP1; ZBED2; EZH1; HMGA2; TLX1; SSX7; ZBTB48; HIPK2; CREM; ERBB4; ZNF562; ZNF343; ZKSCAN8; REL; ZNF467; GON4L; ZKSCAN5; TAF1; RNF14; ASCL3; ZSCAN32; PAX6; ASH1L; FOS; SCAI; WNT4; MXD1; CBL; NEUROD6; SMARCD2; SSX1; PPARG; RCOR3; EYA3; IKZF2; CARF; ZKSCAN1; TBR1; ZBTB39; NHLH1; FOSB; NKX2-5; HNF4G; WHSC1L1; ZNF492; TFEB; ZNF682; LIN28A; ZNF430; DCC; IRF6; NHLH2; DACH1; YBX2; MYCL; E2F2; NR1H2; ATF7; JUNB; ZNF391; ZNF273; NFX1; GRIP1; ZNF286A; ZNF770; ZNF253; RFX3; ZNF571; LHX1; ZKSCAN4; CDK8; SSBP3; ZNF556; SSX3; ACTL6B; NR6A1; KAT2A; ZNF442; TAL1; FOXA2; NEUROD2; FOXH1; ZHX3; ZNF816; ZFP2; ZNF200; POU2F3; ZNF257; LHX3; TMF1; ATOH1; ZNF695; BCL11A; FEZF2; ZNF516; AFF4; HIF3A; ARL2BP; ARID3A; SALL2; TSC22D3; ZNF549; SIX3; RNF141; JUN; NKX3-2; ZIC4; AFF2; PDX1; ZXDC; NR2E1; SSBP2; SRY; TBX3; TRIM25; ZNF611; THAP11; ZFP69B; CEBPD; ZNF154; TERF2; POU6F1; FOXJ1; SATB2; CHD2; ZNF34; NR2F1; ZNF710; MED31; HOXA2; VGLL1; ZNF221; ZBTB3; IKZF3; ZBTB7B; PHIP; TAF4B; KAT2B; POU2F2; NFE2; EMX1; ZNF384; KLF8; IRX5; ZNF132; PAX4; EPAS1; OVOL2; PBX2; MDM2; HSF4; MNX1; PROP1; ZNF507; ZNF157; ZIC3; NANOG; ZIM2; ZNF780B; MAML3; CALCOCO1; ID1; SOX21; RSF1; MYRF; NR1H4; SOX17; SIX6; SMARCD1; NR5A2; ZNF500; ZNF665; MDM4; CBFA2T3; ZNF264; NCOA1; NEUROD4; E2F4; SUPT7L; PRDM1; SPI1; RFX1; HOXC11; TFDP3; ZKSCAN3; ZNF107; NR4A1; MTF1; ZNF225; NR4A3; TCF7; HES2; ZNF557; SP4; DLX2; CLOCK; THRB; ZNF214; SHOX; FUBP1; ZNF711; PBX1; HOXC5; ZSCAN2; ZNF688; TBX19; SATB1; PGR; FOXE3; RFXAP; TFAP4; SKIL; ZNF613; TAF1C; ETV3; BRDT; MECP2; ZNF43; ELF3; NEUROD1; SNAI1; ZNF814; EGR1; HOXA6; TULP2; NEUROG2; PAXBP1; CREB1; MKL2; ZNF701; ATF6; ZNF674; ZNF552; TLX3; TAF5L; EHF; AR; TEF; ZNF573; ZNF506; TRIP11; MED25; NR0B2; GCM1; HESX1; TAF6L; TCF21; ONECUT1; GCM2; TULP1; ZNF480; TBX4; CUX2; HOXC4; IRF5; MITF; HIC2; SOX2; VHL; TBX21; ZNF550; TAF12; ZNF85; ZNF471; CHD7; TBL1Y; ZNF440; ALX4; GBX1; ZNF749; FOXF2; WT1; ZNF117; TP73; ZNF80; SOX3; BAZ2B; CBFA2T2; TRIM27; ESRRG; ZNF407; ZBTB43; ZNF667; TCEA2; RXRA; NLK; CAMTA2; SOX5; ZNF248; PROX1; RARG; GLI1; ZSCAN18; ETV6; ALX3; HIPK1; BRWD1; RORB; ZNF426; HOXB8; ST18; ZNF778; NEUROG1; NCOA3; GRHL2; ZNF345; PRDM9; TCF7L2; ZBTB6; ZNF10; ZNF335; KLF11; SOX14; ZHX2; GTF2I; PRDM14; GSC2; CIITA; ZNF813; ZNF235; HOXA1; GATAD2A; BNC1; CDX1; GATA1; HINFP; PAX7; ZNF415; INSR; CRTC1; ZNF652; ZBTB16; ZNF654; E2F6; ZNF141; POU3F3; ASCL2; CRYM; FHL5; MAPK8IP1; SOX18; ZEB1; ZNF394; ZNF276; POU2F1; PHF1; DBP; ZNF143; LHX2; ZNF175; ID4; PKNOX2; DMTF1; ARID3B; MLXIP; SCRT1; NPAS1; ZNF180; NKX2-1; GATA6; POU5F1B; PRDM2; CCNH; ZNF254; ZNF75D; GATA4; GFI1; LHX6; ZNF623; SETDB1; ZNF136; MLLT1; TRIM24; POU1F1; RBL2; YAP1; NR0B1; HOXB5; ZNF675; HLX; VAX2; NR3C2; TBX5; KDM5C; SKI; MYCN; TAF4; ADRB2; PFDN5; ZFHX2; TULP3; PURA; ZNF232; ZBTB20; KLF4; CRX; ZNF91; SRCAP; HOXA3; ESR1; ARID5B; SMAD9; ZNF223; KMT2B; MZF1; CHD9; POU6F2; TGIF2; ZNF131; E4F1; KLF3; HES1; AEBP1; LEF1; MYNN; MEIS2; NAB2; PPARA; PRDM5; TUB; ETV4; HMX1; CREB3L2; TCFL5; BANP; EGR4; CREBZF; CSDC2; RORA; STAT4; NKX6-1; HMBOX1; HOXC8; CBX2; OVOL1; HEYL; ZNF93; MLLT10; CDX2; CDIP1; CBX4; TOX3; NFIB; SALL1; MYT1L; MED12; DLX5; ZNF224; BPTF; FOXL2; TCF3; TULP4; KLF7; PLAG1; MAP3K10; TBX1; PPP1R13L; PNRC1; NR1I2; E2F5; BARX1; PRRX1; IRF9; MNAT1; WWP1; SIAH2; NFIX; TFAP2A; ATF3; HIPK3; HDAC5; ZNF250; AIRE; SOX15; TXNIP; NFKB2; ZNF350; ZSCAN9; CNOT3; KLF5; VDR; NPAS2; ZNF44; FHL2; ZNF83; PAWR; ZSCAN31; CUX1; MNDA; NFE2L3; VPS72; LYL1; PEG3; ZNF532; ZNF160; CSDE1; ZNF165; MED13; SOX13; NFE2L2; FOXG1; ZNF124; MEIS1; PPARD; TLE2; CEBPB; SMARCA1; SOX10; TGIF1; HIRA; HOXC10; HDAC9; IRF8; ATF5; ZNF721; NKX2-2; NFATC4; CDK2; NFAT5; ASCL1; HEY1; KLF13; SPDEF; TCF4; MEF2C; SUZ12; EGR3; IKZF1; CITED2
Down-regulation 164 LOXL2; NUP62; FOSL1; USP22; APEX1; PUF60; PAX8; ATF4; ZFP36L1; UBE2I; CCNA2; HOXA10; XBP1; C1QBP; CCNC; SMARCE1; TRIM28; TFAM; NFKBIA; ATF1; SMARCA4; EZH2; SUV39H1; SREBF1; FOXO3; HMG20B; RBBP4; NONO; TBP; MED4; VGLL4; NCOA4; RAN; CENPF; FOXJ3; TGFB1I1; PTTG1; MED23; CTR9; XRCC6; HOXB7; HNRNPD; DRAP1; PQBP1; FOXD1; FOXM1; BCLAF1; NRBF2; SNW1; RBM14; REST; REPIN1; NFE2L1; CDC5L; ENO1; ASXL1; DDX5; CRY1; SCAND1; DEK; DNAJC2; ITGB3BP; HDAC1; BATF3; ZBED4; CENPB; PCBD1; CRK; NEDD8; SMARCA5; TBPL1; MAZ; ZBTB38; TOX; EDF1; PMF1; ELF4; BTF3; CREB3L1; FOXN3; ZZZ3; COPS2; CBX3; KAT7; MAFF; BIRC2; ERBB2; BASP1; HMGB2; RNF4; YWHAB; EWSR1; HSF2; WWTR1; DDX17; ILF2; MTDH; PRKDC; ZNF593; GTF3A; SFPQ; CARHSP1; FOXO1; TP53; ZFHX4; BMI1; NFIL3; TBL1XR1; TAF10; SUB1; SND1; NCOR2; LPIN2; MED24; MEOX2; BHLHE40; HLTF; C1D; TRIM32; SMAD2; SP100; ARID4B; DR1; BCL3; NPM1; YBX1; RBBP7; TEAD1; CBFB; AATF; SMAD3; DNMT3B; DAXX; UBE2B; BBX; RFC1; NKX3-1; AFF1; PCGF2; CTBP1; SAP30; RNF138; RNF10; FLNA; MED1; SIX1; PDLIM1; ZNF146; ELK3; MAGED1; KAT6B; AHR; ING2; EMX2; MBD2; IKBKAP; HOXC6; FOSL2; MSX1; NR2F2; GTF2A2; KDM5D; TRIP6; SOX11