Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08915 Geldanamycin GSE70138 HA1E Human 24h 3.33uM EID0001
Types Number Response transcription factors
Up-regulation 110 CEBPD; PBX1; ZNF16; TEAD3; CREG1; SP1; EPAS1; CIR1; ZNF219; ZKSCAN4; ZNF263; FOXJ2; PHF1; RERE; ZNF175; SSBP3; HEY2; ZNF227; ZNF384; CALCOCO1; SUPT5H; ZNF467; EMX2; ZNF224; CITED2; TRAK1; ARID4B; BAZ2B; NR2F1; E2F8; TOB1; TAF5; ZNF45; BCL11A; CBX5; SAP18; NCOA1; PIAS1; ATF5; ZNF304; HDAC1; THRA; ZNF444; PATZ1; ZNF580; TCF7L1; PFDN5; SCMH1; TCF7L2; PNRC1; PHIP; SUPT4H1; NAB2; TBX2; COPS5; CENPF; SPI1; TRIM28; MNDA; FLI1; MAZ; JUP; HOXC4; RBPJ; CBX7; CREBL2; SP140L; SND1; BRD8; BRD2; DBP; NR4A2; EYA2; HMGB2; ZNF331; ZNF665; SOX11; JAK2; INSR; ESR1; NR1H2; TOX; KLF5; CALR; ZFPM2; ARNT2; ERBB4; FOXF1; HDAC4; NCOA2; CSDE1; BCL6; HIPK3; TFEC; MYB; NR2F2; TLE4; CBFA2T3; SALL2; FOXO4; OSR2; MYCL; CEBPB; DACH1; RXRA; WT1; ELF3; MECOM; TRIM22; HMG20B
Down-regulation 61 FOSL1; NFKBIA; MYC; RELB; BHLHE40; HIF1A; JUN; NRIP1; ELK3; KLF10; DRAP1; ZMIZ1; RUNX1; DLX2; SOX4; FOXO3; HMGA2; NCOA4; KLF6; BIRC2; BATF3; ENO1; SMAD7; WDR77; EGR1; LOXL2; ETS1; ZNF593; KLF7; NCOR2; SMAD2; TLE1; EGR3; CBX3; CRY1; MAFG; LMCD1; HOXA10; SERTAD2; TRIM29; RAN; NKX2-2; TWIST1; NKX3-1; SATB2; HES1; MLXIP; FOSB; SNAI2; MAFB; STAT3; YWHAB; FOXD1; IRF7; ID1; ID3; EGR2; RUNX3; POU2AF1; SOX9; ZNF423