Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08901 Mitoxantrone GSE70138 HA1E Human 24h 0.04uM EID0001
Types Number Response transcription factors
Up-regulation 29 SUV39H1; NR1H2; FHL2; KAT6B; MDM2; ZNF692; TRIP6; TRIM22; TP63; ATF3; LITAF; TBX3; RUNX3; IRF9; ZNF91; FOXF2; ARNT2; BCL6; HDAC9; ZNF532; TOB1; ELF1; FOSL2; PDLIM1; IFI16; SNAI2; BBX; CITED2; MEIS2
Down-regulation 44 CCNA2; MYC; HNRNPD; MAZ; CCDC59; SMARCE1; CENPF; HMGB2; PSMC3; ID4; SUPT3H; AEBP1; DLX2; HOXC6; ERG; HOXA10; ILF2; NFATC3; GRHL2; RAD21; FOXM1; PITX2; HOXC4; HMGB1; ATF4; RBPJ; THAP11; CREB3L1; LEF1; MYCL; ENO1; MEOX2; PTTG1; NFE2L3; CRYM; MYB; NFE2; KLF2; LMCD1; ZHX2; KLF6; ASCL1; ZNF423; SATB1