Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08900 Mitoxantrone GSE70138 HA1E Human 24h 0.12uM EID0001
Types Number Response transcription factors
Up-regulation 73 TRIM22; TOB1; CDIP1; MDM2; DDIT3; TP63; IRF9; TGIF1; HDAC9; ZBTB48; ZNF7; BCL10; CEBPB; YAP1; NCOA4; TAF12; SP110; IRF8; ETV5; ZNF593; BATF; MNT; SMARCA2; ZNF623; ZKSCAN1; ZNF14; SNAI2; TRIB3; KDM5D; SP140L; BANP; ZBTB16; RNF6; EPAS1; ZNF430; NAB2; CBX6; MITF; ZBED1; SIAH2; SERTAD2; ZNF268; ING2; MAX; BAZ1A; PEG3; PHF20; TRPS1; TRIP6; RBBP7; MXI1; TXNIP; VDR; HIRA; PCGF2; RUNX3; SP100; KLF10; TSC22D1; TBX3; EYA2; MAF; TCF7; LITAF; SOX9; PDLIM1; BHLHE41; TWIST1; ZBED2; ARNT2; MEIS2; AHR; ID1
Down-regulation 68 CCNA2; MYC; CENPF; PARP1; HNRNPD; PAXBP1; MAZ; TAF5; SMARCE1; FOXM1; HMGB1; ORC2; CENPB; DLX2; XRCC6; SFPQ; PITX2; TLE4; CBFB; CHD7; CARM1; E2F8; TAL1; SSRP1; PSMC3; SF1; ZNF32; E2F5; HMGB2; ERG; WWP1; NELFB; PTTG1; TAF9B; THAP11; CALR; MYCL; FLI1; ASXL1; NR4A1; KLF2; ATF4; PIAS1; ZNF22; SMAD6; RUVBL2; ELF3; BNC2; CRYM; ID4; TCF4; FOSB; MECOM; NR2F1; GATA6; AEBP1; POU4F1; MEOX2; ZNF423; INSM1; KLF6; LMCD1; NR2F2; CITED2; TOX3; SOX11; HOXC6; SATB1