Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID08899	Mitoxantrone	GSE70138	HA1E	Human	24h	0.37uM	EID0001

Response Information :

Types	Number	Response transcription factors
Up-regulation	107	ZNF211; IRF9; TRIM22; MDM2; TP63; TOB1; DDIT3; TSC22D3; TSC22D2; FOS; SUPT7L; FOSL1; CEBPB; CDIP1; STAT1; NCOA4; GATA2; ZNF79; TRIM29; SNAI2; ZBTB43; ZNF529; SREBF1; ZNF419; ATF3; JUNB; ZNF304; SRCAP; ZNF692; RUNX3; EGR2; ZKSCAN1; SOX4; MITF; ZNF672; MAFG; ZNF430; ZNF266; YBX3; DDX5; NAB1; CBX6; SCAND1; ZNF394; ZNF91; HLX; RCOR1; RNF6; STAT3; MNT; BCL10; PLAGL2; PDLIM1; ZNF432; MAF; TAF1D; ETV5; JUP; ZNF468; ZNF665; REL; TBX3; FOXN3; AHR; ZNF189; SP110; TOX; KLF5; IRF7; PHOX2B; BCL3; MSX1; PEG3; KLF11; EPAS1; SERTAD2; BHLHE40; ZNF593; BCL6; ZBED1; ZNF160; ZNF195; RUNX1; ARNTL; RXRA; ZNF264; FOSL2; NFAT5; KLF4; EMX2; OSR2; CREBL2; HOXD1; NFE2L1; KLF10; ZNF331; ETS2; SOX9; ELK3; ID1; TCF7; DACH1; IRF8; BHLHE41; PIR; NFATC3; ADRB2
Down-regulation	106	MYC; CCNA2; CBX5; MYBL2; ECD; PARP1; SMARCC1; UBE2I; CENPF; ID4; SUB1; HNRNPD; FOXM1; CLOCK; USP16; PITX2; GABPB1; PCBD1; SSRP1; NR2F1; SMARCA4; CAPN15; PRMT2; BRD7; GLI2; TBL1XR1; TAF5; DLX2; KMT2A; NR3C2; ESRRG; HDGF; ARL2BP; CREB3L2; HOXC4; AGO2; SOX12; HMGB2; TEAD4; CARM1; RHOA; BNC2; MAZ; CBX3; PA2G4; BCLAF1; ASCL1; BLM; MYBL1; SUPT3H; CNOT2; HMGB1; NPM1; SALL1; PTTG1; CARHSP1; CSDE1; TLE4; ZNF711; BACH1; ZBTB20; NFE2L3; ZFPM2; RAD21; LEF1; TGFB1I1; E2F5; ZEB1; CALR; NR4A1; MEOX2; KLF6; TCF21; WWP1; CITED1; MBD2; NR2F2; SLC2A4RG; NLK; CBFA2T3; RBPJ; GATA6; RORA; FOXD1; WT1; HOXB6; IRX5; LIN28A; CHD7; ZHX2; SOX10; INSR; POU2AF1; INSM1; HOXC6; MYRF; KLF2; PSIP1; MEIS2; NKX2-1; ZNF423; AEBP1; FOXF1; ZBTB18; ABL1; MNDA