Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08898 Mitoxantrone GSE70138 HA1E Human 24h 1.11uM EID0001
Types Number Response transcription factors
Up-regulation 246 IKZF1; MDM2; ZNF211; SNIP1; TSC22D3; TCEA2; TOB1; ZNF45; ETV5; ZNF274; THAP10; ZNF43; ZNF140; ZNF557; ZNF606; ZNF222; ZNF14; SNAI2; ZKSCAN7; CDIP1; TP63; CEBPD; EGR4; RUNX3; NHLH2; ZBTB43; MED17; ATF5; ZNF268; SIX3; ATF3; DDIT3; MLXIPL; SUPT7L; ZNF200; KLF11; TRAF6; TAF1C; ZNF419; BRD2; ZNF79; ZNF3; EN1; ZNF23; ZNF227; ZNF544; ZNF10; EGR2; BRF2; ZNF235; ZNF180; ZNF350; ZSCAN9; MTF1; MBD1; ENY2; PRDM1; ZNF468; ZNF415; ZNF195; NHLH1; TOX; TGIF1; ZNF473; BCL10; ZNF8; TRIM29; PRDM4; HLX; ZNF84; ZNF304; ZKSCAN4; ZNF354A; ZNF75D; ZNF430; TBX21; SUPT4H1; ZNF232; TCF7L2; PHOX2B; ZSCAN32; ZNF134; HBP1; IRF9; GFI1; MYT1L; ZNF816; ZNF324; ZNF175; ZNF35; ING4; HINFP; ZXDC; CREG1; TAF4B; BATF; ZNF85; ZNF529; IRF6; ZNF141; ZNF432; L3MBTL1; HOXD1; TSC22D2; MAK; ZNF273; PEG3; ZKSCAN5; HAND1; TRIM22; PHF1; DBP; SOX3; MEF2C; HTATIP2; REL; ZNF426; STAT4; ZNF189; ZNF331; PNRC1; GABPA; ZNF44; KDM5C; TAF11; ZEB2; PCGF3; CD3D; NR4A2; CEBPB; TCF7; PPP1R13L; LHX2; CBX4; ZFPM2; ZNF267; TTF1; LHX3; ZNF136; ZNF212; TFDP2; GCM1; JUP; ZKSCAN8; SAP18; ZNF654; TWIST1; STAT3; LHX6; TFAP2A; HCFC2; ZNF223; HES1; ZNF117; ZNF184; ZNF665; TCEB2; SIN3B; THAP1; ZNF253; RSF1; ZNF7; MXI1; RNF4; ZBTB7A; HEY1; ZNF93; YBX3; BCL6; PFDN5; KLF5; DACH1; ZNF264; TDP2; ZNF623; IRF1; ARNTL; SP140L; EPAS1; NR4A3; KLF4; FOXF2; STAT2; ZNF394; RNF6; HOXA1; CBX7; CAMTA1; TAF7; AR; ZNF12; JUNB; MAF; SP2; EMX2; ARNT2; ZKSCAN1; LITAF; CERS6; BRD8; VDR; INSR; BCL3; TRIB3; GATA6; VPS72; HMGB3; ZNF266; ST18; ZNF22; TBX3; SHOX2; ZNF107; SSX1; TFAP2C; ZNF536; MYRF; CUX2; MAFB; CREM; NFE2L1; OSR2; ZNF423; EGR1; FOXO4; SPDEF; NR1H4; TXNIP; ZNF83; PBX1; ZBED2; SOX9; FOXO1; FOSL2; CITED2; PIR; ZNF91; RXRA; MECOM; TRPS1; GATA3; ADRB2; AHR; MNDA; TSC22D1; SATB1
Down-regulation 125 PAX8; PARP1; ECD; HNRNPD; MYC; CCNA2; SMARCA4; SMARCC1; XBP1; CENPF; NFKBIA; HOXA10; MYBL2; PRMT2; CBX5; CBFB; TBL1XR1; CUX1; GABPB1; PCBD1; CBX3; ORC2; STAT6; TCERG1; MMS19; SSRP1; MAZ; PRKDC; ADNP2; UBE2I; TGFB1I1; BCLAF1; ARNTL2; SPEN; GTF2IRD1; RERE; TEAD4; KLF6; SUB1; GLI2; PITX2; NR2F2; IKBKAP; RHOA; WHSC1; FLNA; HMGA1; HIVEP2; LOXL2; SF1; BRD7; CREB3L2; AFF1; ENO1; PTRF; NRIP1; BLM; BRD3; HDAC1; ZMIZ1; CSDE1; NELFB; SMARCA5; SP3; C1QBP; TGIF2; TRIM28; SFPQ; E2F5; ZMIZ2; REPIN1; MAGED1; HDGF; NONO; ZBTB1; NFKB1; CARM1; FOXC1; DEK; FOXD1; BNC2; HMGB2; DNMT3B; NEDD8; CREB1; RBPJ; TCF12; THAP11; MLXIP; CARHSP1; MYBL1; WWP1; CREB3L1; ATF4; PCGF2; DEAF1; URI1; ZFP36L1; ZNF131; HOXC6; RBPMS; WWC1; SALL1; CRYM; CALR; PAWR; SP100; PSIP1; AEBP1; SMAD1; YWHAB; TOX3; ID4; TBL1X; ZBTB38; HOXC10; MNAT1; APEX1; MEIS1; ABL1; KDM5D; ERBB4; STAT5B; ESR1; NR3C1