Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID08896	Mitoxantrone	GSE70138	HA1E	Human	24h	10uM	EID0001

Response Information :

Types	Number	Response transcription factors
Up-regulation	111	HDAC9; PSMD9; TCEA2; NFIX; MEF2C; NFKB2; GTF3A; GCFC2; CLOCK; MED25; OVOL2; VGLL1; PROP1; SIX3; WDR77; PRDM12; GBX1; GATAD2A; ESRRG; MYCBP; SMARCB1; HMGA1; HOXB1; ZNF528; BRD4; LHX3; GFI1B; GATA1; HSF1; NKX3-2; PRDM14; SRCAP; CARHSP1; TSHZ2; ATN1; HIPK2; MED12; BCL11A; CDX1; FOXA2; SETD3; IRF6; ZNF816; ZNF467; TBX1; TCEA1; BARX1; E2F5; E2F2; ZIC1; SSBP3; ETV5; HDGF; ZNF667; INSR; KAT2B; HAND1; CNOT3; FOXM1; CERS6; ZNF580; MYCL; NKX2-2; ARNT2; EN1; ZNF415; CBFA2T3; PAX6; GRHL2; SPIB; WNT4; URI1; TCF7L1; CUX2; VPS72; SPDEF; CSDE1; HOXD1; MECOM; SMARCA1; TWIST1; CEBPG; TRPS1; ZNF665; TAL1; JUP; SLC2A4RG; ZNF91; SIX2; ZNF532; PLAGL1; EHF; CD3D; ZNF264; POU4F1; SATB2; FOXG1; MXI1; MEIS2; SOX17; EYA2; PEG3; PITX1; PBX1; ERBB4; ZBED2; EMX2; ESR1; MAF; DACH1; KDM5D
Down-regulation	122	NFKBIA; MYC; SUV39H1; NFIL3; ARID5B; FOXJ3; CDK7; FOSL1; CCNA2; MED17; TBPL1; HOXA5; MTF2; TBP; ARID4B; SOX4; FOXO3; EED; NUP62; BHLHE40; JUN; ZBTB11; SMAD7; BRD8; ID2; ATF1; AFF1; ZBTB1; BTG1; NPAT; RBM14; SNIP1; PATZ1; HOXA10; XBP1; DDX5; TGIF1; TAF1D; CEBPZ; BIRC2; TSC22D2; ADNP; ZNF146; KMT2A; RNF111; CHD1; ZMIZ1; EGR2; DPF2; MGA; TAF9; HMGXB4; MAGED1; KLF2; BAZ2B; HSF2; EGR3; JUNB; PHF20; IRF2; TRIM32; SMAD3; BCOR; NCOA4; ZNF292; NRBF2; BASP1; CENPF; TRIM16; TBL1XR1; SPEN; ZNF410; MED6; ZNF217; ING3; MYT1L; TOB1; ELF1; EGR1; RLF; HOXC6; TBX3; CHD7; ILF2; BAZ1A; KDM5B; VEZF1; ZNF267; NKX3-1; YWHAB; ZNF281; HMGB2; VGLL4; PCGF2; NFKB1; EDF1; ASXL1; KLF6; IFI16; DNMT3B; JARID2; TLE4; FOXO1; ZNF165; CHD8; FOSL2; ZBTB18; HHEX; KLF10; HMGN3; TLE1; ZNF131; ZEB2; ENO1; AHR; HES1; BMI1; THAP11; SOX9; ID3; TXNIP; NR3C1