Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08879 As-601245 GSE70138 HA1E Human 24h 3.33uM EID0001
Types Number Response transcription factors
Up-regulation 588 CEBPD; SIX3; NR2E1; IKZF1; FOS; TULP1; CD3D; NFIX; TCEA2; ZNF117; AR; PDX1; ZNF154; TP73; SSBP3; PRDM14; THRB; HOXB8; DCC; ZNF771; ZNF8; TBX5; LDB1; ZNF787; BCL11A; ASH1L; POU6F2; TBX21; PRDM9; ZNF10; ONECUT1; RFX1; NEUROD4; MAML3; HES2; ZNF235; TEF; CHD2; TBX19; ZNF221; PROP1; IKZF2; FOXE3; KLF15; SOX21; HSF4; MEIS2; ALX4; LHX3; GBX1; THRA; VENTX; TBR1; ALX3; ZNF695; NEUROD6; FEZF2; SRY; GRIP1; SCAI; NEUROG2; TBX4; ZNF549; SCRT1; POU3F4; FOXL1; DLX5; AIRE; SSX7; ZNF43; RBPJL; RORC; IRF6; POU2F3; HEY1; NR5A2; MEF2C; POU1F1; ZIC4; HIPK2; HIF3A; DLX6; ZNF345; ZFY; NEUROD2; ZNF814; ATOH1; ZNF749; TBX6; OVOL2; HDAC9; ZNF544; TFDP3; ATN1; MDM2; HOXB1; ETV3; ZNF132; EYA3; HOXD12; HOXA3; ZNF391; CBX2; ACTL6B; HAND2; NR5A1; CDX4; HIVEP3; MAPK8IP1; ASCL3; ZNF816; MAK; PAX1; ZNF350; NKX3-2; CRX; PRRX1; SOX14; MSX1; ZFHX2; VGLL1; VSX1; BARX1; SRCAP; ZNF442; DOT1L; SP4; ZNF778; BRDT; PRDM2; ZNF208; ZFHX3; SHOX; GSC2; ZNF180; ZNF467; TULP2; ZNF343; SPIB; ZNF550; ESRRB; ATF6B; NOCT; FOXP3; FOXD3; ZNF471; HDAC5; MED25; NEUROG1; E2F2; ZIC3; NKX2-5; AFF3; SPI1; FOXB1; TLX3; IKZF4; ZNF287; TONSL; ZNF507; CREG1; TBL1Y; FOXH1; TLX1; EMX1; LBX1; NPAS1; PAX3; ZKSCAN8; ZNF81; KLF8; THAP3; CNOT3; ZNF362; RFX3; TBX10; CARF; ZNF407; ZFP2; POU4F3; CAMTA2; PRDM8; NKX6-1; PAX7; FOXA2; IKZF3; AFF2; SIX6; VPS72; ETV2; PRDM5; ZNF225; GTF2A1; ZNF253; TGFB1; ZNF254; FOXG1; ZNF780B; ZNF211; HOXC5; CALR; HESX1; PAX4; ZBTB7C; JUP; GCM2; ZNF669; ZNF273; ZKSCAN4; ZNF606; ZNF331; ZNF74; ZNF257; ZSCAN2; ZNF85; OVOL1; FOXF1; CBX8; FOXN1; MLLT1; TAF4B; SOX18; ZNF667; PRDM12; ZNF674; ZNF556; ATF7; MYEF2; NR4A3; SOX1; SOX5; TAF7L; HMGXB3; ZNF34; ZNF529; POU3F3; ZNF440; ZNF557; ZSCAN9; ESR2; RORB; TSHZ2; ZNF835; PITX3; ZNF224; HIC1; TAF6L; ZNF484; RING1; CDIP1; MDM4; ZNF219; ZNF701; NACA2; DBP; NR6A1; ONECUT2; CDX1; MYNN; RORA; MAFK; SOX2; SOX3; SMARCD1; MAP3K10; ZNF223; HOXC8; MSX2; ZNF710; ZNF141; HDAC11; NR4A2; ZNF551; ZNF174; TCF21; HNF4A; ZNF480; ZNF304; ZNF682; MTA2; SNAPC4; ZNF155; PRDM13; SIX5; ZBTB7B; ZBTB32; HOXB5; MZF1; GBX2; HEYL; ZNF264; ZNF136; SALL2; MBD4; NR1I3; ZNF460; POU3F2; ZNF80; FOXJ2; CIITA; WHSC1L1; ZNF91; ZNF573; E2F4; ZNF124; ZFP69B; TWIST1; RARG; NHLH1; NFATC4; PEX14; TUB; ZNF41; NR1H2; NHLH2; EN1; ZBTB3; PPARA; CEBPE; SOHLH2; FOXJ1; MED12; E4F1; ZNF571; ASCL2; DLX2; TOX; ZNF214; EYA1; ARID3B; LZTR1; RAX; CRTC1; VHL; PBXIP1; ZKSCAN3; EGR4; ZBTB44; PRDM10; HOXD13; KLF13; ZNF234; SPDEF; KAT2B; ZNF197; EMX2; ESR1; SKIL; HOXB13; TAF1C; ATF3; HNF4G; ZNF493; ZNF134; HMX1; EHMT2; NEUROG3; THAP9; SLC2A4RG; LHX6; ZNF157; MYT1L; TAF1; ZNF675; ZXDC; BRF2; NR4A1; SOX17; PKNOX2; FOXF2; ING4; KAT2A; FOXI1; CERS6; ZBTB48; RUNX2; CCNT1; EVX1; ZNF93; ZNF415; CBX4; MYCL; ZNF671; ZNF589; SETDB1; ZNF75D; SSX3; TFAP2A; GATA2; BNC1; ZBTB17; PPARD; RFX2; CHD4; EPAS1; PBX2; ZFP37; DMRT1; GFI1B; ZNF613; SNAI1; TRIB3; STAT4; GCM1; HLX; FOXN2; ZNF334; CUX2; KDM5C; UTF1; ZNF286A; CAMTA1; PAX6; HAND1; GFI1; ARNT2; PCGF1; ELK4; CRYM; FOXC2; EP300; ZNF423; ZNF205; L3MBTL1; ZNF44; WNT4; PRDM1; KDM4C; GRHL2; ZNF813; FHL5; GATA1; ZNF135; SOX15; ST18; RSF1; IFNB1; EN2; LIN28A; NFAT5; RHOA; EGR1; CDX2; RBFOX2; RXRG; BHLHE40; ZNF500; ZNF358; SMARCB1; ERBB4; MNX1; ISL1; ZNF444; ZNF492; HOXA2; ARID5A; LZTS1; SHOX2; ZNF688; TCF7L2; TERF1; ZNF222; REL; ZNF215; ZNF711; DLX4; ZNF665; ARRB1; TEAD3; SMAD5; ZNF394; TCF4; MNDA; CBX7; NAB2; ZNF133; SALL1; ZNF175; SOX13; NFIC; MTF2; CIR1; POU4F2; ZNF646; PLAGL1; MXD1; MYOG; KLF1; MEF2D; ZNF506; NR2F1; CALCOCO1; MYT1; JUNB; ARID1A; MYF6; FOXA1; ZNF112; TAF6; THAP10; NR1H4; ID2; CREM; CBFA2T3; MEOX2; ZNF580; EYA2; POU2F1; ZNF14; TSC22D3; NFATC1; ETV1; HIRA; YBX3; SOX11; AFF4; ID3; BCL3; IRF8; ZFHX4; ZNF536; PBX1; HOXD10; SMAD7; NEUROD1; NANOG; BRD4; GLI3; ZFPM2; MECOM; HDGF; NOC2L; LEF1; BCL6; HOXD3; ZBED2; GTF2I; E2F5; NKX2-2; RERE; TRIM24; TCF15; ZNF232; ID1; HOXD11; TDP2; INSM1; ZNF195; NR1H3; HEY2; WT1; MYCN; FOSB; ZNF239; CNOT2; HLF; JUND; TRPS1; MXI1; PAX5; PITX1; HIC2; POU2AF1; GATA6; ZNF83; ZNF611; BACH2; HMBOX1; TCF7; TCF7L1; OSR2; RUNX3; YAP1; LITAF; HOXB2; AEBP1; ZSCAN18; ZSCAN31; SATB2; SSX1; HOXD1; VDR; OLIG2; ZIC1; TSC22D1; NKX2-1; TRIM22; BHLHE41
Down-regulation 182 XBP1; FHL2; CCNA2; PAX8; USP22; SUV39H1; ATF1; HNRNPD; TP53; TBP; NUP62; CBX3; BRCA1; SUZ12; SNW1; MYBL2; ZNF146; SFPQ; TSC22D2; BRD3; BAZ1A; AFF1; NPAT; PUF60; RBM14; ZMYM2; UBE2I; SMARCC1; VEZF1; EED; HOXA5; HOXC6; ERBB2; SMARCE1; PQBP1; NPM1; SOX4; PREB; ECD; SMARCA5; EZH2; FOXO3; REST; RB1; PATZ1; PSMC3IP; SMAD3; TBPL1; BLM; WHSC1; BASP1; HIF1A; TRIM29; CRY1; NCOA6; PHIP; BRD7; CCNC; ATF5; GTF2A2; HTATIP2; ITGB3BP; BRD8; HOXA10; TRIM32; NCOR2; RUNX1; STAT1; ZNF302; MED13; RBL1; PHF20; DEK; MED7; TAF9; TRIM16; AATF; ZNF217; KMT2A; MED1; HOXC10; HDAC2; IRF7; RBBP4; UBE2B; KDM2A; NAB1; RNF14; NELFB; BRIP1; BMI1; PURA; EDF1; RNF111; BCLAF1; HSBP1; DDX5; ATF6; HSF2; ING2; CENPF; ENO1; TRIM27; GTF2IRD1; ORC2; CNOT1; RAN; ZNF189; CHD9; RREB1; SF1; ZBTB38; RFC1; DNAJC1; CARHSP1; CNOT6; NFIL3; MED6; ELF5; COPS5; ARID4B; HMGB2; ZMIZ1; NRBF2; CBFB; CTR9; HOXB7; ELF1; TRIP6; CDK8; MBD2; SMARCA2; JARID2; IFI16; CCNE1; SAP30; TAF10; KAT7; ATF4; PBX3; YWHAB; GATA4; E2F3; ZBTB18; MAX; NR2F2; PCGF2; SOX10; MAGED1; WWC1; CTBP2; BTG1; NFIB; TBL1XR1; RBBP8; KLF6; STAT3; FLNA; CREB1; RBPMS; HMGB1; MYB; PTRF; NKX3-1; PTTG1; LMCD1; CRK; ETS2; TFAP2C; MNAT1; KLF5; SIAH2; TLE1; ELK3; TBL1X; TCF12; NPAS2; TOX3; TLE4; ZNF652; FOXC1; STAT5B