Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08878 Linsitinib GSE70138 HA1E Human 24h 0.12uM EID0001
Types Number Response transcription factors
Up-regulation 29 UIMC1; TBX2; MEOX1; CCNC; DEK; ID4; EPAS1; CALR; ZBED2; SNAI2; KLF9; SUMO1; TP63; SATB1; MECOM; NR4A3; HMGB1; EMX2; ZSCAN18; MEIS1; ZNF160; ZBTB38; ZNF331; LITAF; NR4A2; HEY1; FOXF1; ZNF91; SOX11
Down-regulation 40 BAZ2B; NCOR2; WNT4; TFAP2C; NKX3-1; MED23; IKBKAP; DLX2; THAP11; PIAS4; NFE2L3; KLF13; BCL6; ZFP36L2; FOXO1; PBX3; HOXC6; FOXA1; CNOT2; IRF1; SREBF1; RREB1; CTBP2; LMCD1; OSR2; ELF3; SP110; IRF8; SOX9; TBL1X; NR2F2; CEBPB; PITX1; RXRA; NCOA3; AEBP1; POU2AF1; TRPS1; KDM5D; ADRB2