Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08876 Linsitinib GSE70138 HA1E Human 24h 1.11uM EID0001
Types Number Response transcription factors
Up-regulation 34 E2F2; STAT5B; VGLL4; LHX2; ZNF227; ZNF177; EYA2; RSF1; ZBTB18; TSC22D2; PBRM1; NR3C2; ZNF184; ZNF131; WNT4; CHD7; NR4A2; LPIN2; EDF1; PLAG1; IFI16; TOX; REPIN1; MYCL; SIX2; DACH1; HLTF; SATB1; ELK3; AEBP1; SOX9; SATB2; MEIS2; MAFB
Down-regulation 17 LYL1; HDAC9; PRDM1; TLE4; IRF9; HHEX; MYRF; CRYM; JUP; CD3D; TCF7; ID4; TRIM29; PBX1; ID1; EGR2; TRIM22