Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID08875	Linsitinib	GSE70138	HA1E	Human	24h	3.33uM	EID0001

Response Information :

Types	Number	Response transcription factors
Up-regulation	53	TBX2; EGR4; SMARCB1; SRF; ING2; ZBTB38; NR4A3; TCF21; DNAJC2; EHMT2; MEIS1; ZBTB1; SKIL; BCLAF1; FOXF1; ZFHX3; CREB3L1; TOB1; SAP18; SMAD7; OSR2; ZBED2; RBPMS; BCOR; YBX3; KLF5; BHLHE40; REL; GRHL2; INSM1; ZNF165; FOSL2; TRIM29; RBPJ; EMX2; EDF1; PDLIM1; ZIC1; TP63; GATA6; CREM; NKX3-1; FOXG1; NR0B1; FOXF2; PITX1; SNAI2; PBX1; TBL1X; NR4A2; TBX3; CREB1; PAX5
Down-regulation	40	CEBPB; ZNF43; NPAT; ZNF232; NFIB; CERS4; LEF1; TERF2; NFE2L3; TRIM22; BIRC2; ETV5; BCL10; ELF1; TFAP2C; ZNF593; ARNT2; ZBTB20; ZBTB16; ZBTB18; MYBL1; KAT2B; JUND; GTF3A; MNDA; ESR1; HOXB2; SOX17; ASCL1; INSR; KLF2; ZNF264; HMGA1; HHEX; ZEB1; MAFB; SMAD1; ZFP36L2; SOX9; AEBP1