Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08873 Ruxolitinib GSE70138 HA1E Human 24h 0.04uM EID0001
Types Number Response transcription factors
Up-regulation 59 GLI2; MED1; PPARG; MEOX1; ZBTB38; PRRX1; ZNF124; EGR3; CEBPZ; ZBTB6; TCF4; NCOR2; CREB3L1; DEK; TXNIP; THAP1; MKL2; RBBP5; TCF7L2; HSBP1; ZMYND11; ID4; OLIG2; CREBL2; CUX2; HEY1; NR0B1; RBPJ; HLF; TCF12; TBX3; TRIM16; FOXO1; NFIB; SMAD2; ZIC1; ZFPM2; ZSCAN31; SOX11; WWTR1; KLF9; ZNF22; ELK3; SHOX2; NR1D2; EGR2; NKX2-1; HIPK3; SATB2; PBX1; SOX9; MECOM; ASCL1; ID3; TOX3; ZBTB18; DACH1; POU2AF1; MAF
Down-regulation 37 LYL1; DDIT3; POLR2A; PHF1; SUPT3H; HOXB7; IRF1; SIX2; MTA1; PHF20; ZNF593; NR2C1; HMG20B; HOXB2; FOSB; FOXC1; SOX10; BCL3; NR4A1; TRIM29; HOXA1; SREBF1; ATF3; PBX3; JUP; SNAI2; JUND; NFE2; HOXC6; NKX3-1; TCF7; TFAP2C; RUNX3; ZNF652; ARNT2; AHR; SATB1