Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08872 Ruxolitinib GSE70138 HA1E Human 24h 0.12uM EID0001
Types Number Response transcription factors
Up-regulation 50 CEBPZ; REL; MED21; ZNF394; HIVEP1; TCF4; ZNF124; PIAS2; EHF; TRIM16; TRIP6; TAF9B; RNF14; KAT6B; CNOT3; MED4; PIAS3; RBBP5; SAP18; MED6; FOS; STAT2; ZKSCAN1; MEIS1; SMAD5; E2F5; GTF2I; ZNF430; EMX2; TFEC; VPS72; ID4; CITED2; CALR; ZNF652; PBX1; NR1H3; ZNF107; YBX3; TOX; ZNF264; TSC22D1; CRYM; PAWR; SOX11; INSM1; PAX5; PLAGL1; ZNF91; TOX3
Down-regulation 59 ERBB2; PRDM2; PKNOX2; INSR; SMARCC1; RARA; ZNF423; BRD2; EYA1; TGIF2; TBX3; SSRP1; LEF1; RXRG; HMGA1; MED1; SIM2; PRRX1; SP100; SP3; THAP11; HOXC6; ASCL1; FOXN3; ETS1; HOXD3; PDLIM1; ZNF217; RORA; AEBP1; HOXD1; NR2F2; MECOM; HOXC10; STAT5A; BRD4; EN1; FOSB; SOX10; TCF7; ATF3; ZHX2; ZFP36L1; HMBOX1; KLF2; ISL1; SMARCA1; ZEB1; IFI16; HHEX; PBX3; SNAI2; PEG3; MAFB; HEY1; PIR; TRIM22; ELK3; MAF