Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08869 Ruxolitinib GSE70138 HA1E Human 24h 3.33uM EID0001
Types Number Response transcription factors
Up-regulation 42 TCFL5; CEBPZ; JUN; THAP10; INSR; BCL11A; IFI16; HHEX; MEF2C; ZNF573; AR; ZNF654; TRIB3; CREB5; NR3C2; HIRA; ERG; EMX2; SOX17; NANOG; PBX1; SALL2; LIN28A; ZBTB16; YBX3; CBFA2T3; WT1; LEF1; SOX11; HEY2; NKX3-1; SPDEF; NR2F2; TFEC; IRF8; ARNT2; MNDA; KDM5D; ZNF423; ESR1; BHLHE41; HOXC6
Down-regulation 44 BHLHE40; ENO1; IRX5; NCOR2; ZNF586; PRRX2; NUP62; RELA; TFDP2; BTG1; PEX2; RAN; IRF4; STAT3; ASCL1; SMARCA2; ATF4; KLF9; RARA; GTF2IRD1; STAT5A; ID1; ZIC1; LPIN2; ZEB2; NR1D2; ELF5; CTNNB1; SIX1; HLTF; EYA1; NKX2-1; TRIM29; HMGN3; FOXD1; PDLIM1; NR2F1; SERTAD2; KLF6; SOX9; FOXC1; PAX6; AHR; SATB1