Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08868 Ruxolitinib GSE70138 HA1E Human 24h 10uM EID0001
Types Number Response transcription factors
Up-regulation 86 ZNF529; MTF2; CAMTA1; THAP10; PBX1; TRIB3; HIPK1; ZFHX3; THRA; CBFA2T3; BRWD1; L3MBTL1; PHIP; FOXF1; NKX3-2; SALL2; ZNF227; SAFB2; ZNF500; TBX2; TCF21; BCL11A; CERS6; ING4; ZNF112; NHLH2; ARNT2; SOX11; FUBP1; TCF7L2; REL; RBBP7; MEIS1; HEY2; ZNF83; HHEX; BAZ2B; ZFPM2; TBL1XR1; IRF9; CBX7; ZBTB20; ZNF248; ZNF711; GRHL2; PCGF2; MNDA; ST18; LEF1; ZNF536; KLF4; TBX3; ZNF302; TFAP2C; MED23; IRF6; NKX3-1; FOXA1; NR2F1; INSR; TCF7L1; HEY1; TERF2; TLE2; SALL1; CTBP2; CEBPB; EMX2; HTATIP2; ZKSCAN1; DACH1; SOX9; ZNF721; EHF; MYB; TLE4; NR4A2; LITAF; TFEC; ETS2; ID3; ESR1; ZNF91; BHLHE41; HMG20B; TSC22D1
Down-regulation 33 MYC; ALX1; MED1; XBP1; HOXA10; NCOR2; BHLHE40; SFPQ; RFX5; ASH2L; PITX2; NR1D2; CRY1; ATF4; FLNA; IRF4; AFF1; CREB3L1; KLF13; STAT3; ENO1; LPIN2; TRIM29; SIX1; PDLIM1; ZBTB38; PTRF; KLF10; MAFB; NFATC3; RXRA; STAT5B; SATB1