Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID08866	Alpelisib	GSE70138	HA1E	Human	24h	0.12uM	EID0001

Response Information :

Types	Number	Response transcription factors
Up-regulation	71	E2F2; TBX21; MED1; PPARG; ZMIZ2; HDAC6; BCL3; TCF4; KLF12; NR3C1; TTF1; STAT4; IRF4; MED24; RHOA; ZNF131; ING3; SMAD7; HOXA11; NR2F1; OLIG2; FOXD1; LITAF; FOSB; SP2; ID2; MAFF; MED13; VPS72; ZBED2; TRIP6; HBP1; ZKSCAN1; HMGB3; CDYL; FOXG1; NR4A3; SATB2; BATF; JARID2; SMAD5; YBX3; JUNB; SMAD2; LPIN2; MYCL; IRF7; BHLHE40; SSX1; KDM5D; CD3D; NR1H3; PDLIM1; EGR2; SATB1; ZBTB38; EGR3; RUNX3; INSM1; HOXC10; SOX11; MXI1; MEIS2; PLAGL1; POU2AF1; RBPMS; ZEB1; ELK3; ID3; BHLHE41; HMG20B
Down-regulation	46	TBPL1; LYL1; RCOR3; MED21; TFDP1; USP22; CCNH; PQBP1; TOX4; CARHSP1; ISL1; THAP4; ENY2; DDIT3; APEX1; CBFB; ZNF593; MTF2; CCNE1; ZFP30; LEF1; DMTF1; ZNF512B; TFAP2C; KAT6B; HAND1; HDAC9; MED23; ZNF93; HHEX; WWC1; CHD8; YAP1; ARNT2; SNAI2; GRHL2; ZMYND8; CALR; INSR; HOXD1; MAFB; CEBPB; MNDA; WT1; TXNIP; GATA2