Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08863 Alpelisib GSE70138 HA1E Human 24h 3.33uM EID0001
Types Number Response transcription factors
Up-regulation 27 SMAD4; YBX3; CAMTA1; ERG; INSM1; TSC22D2; EDF1; CHD7; HMGB3; ZBTB20; KLF6; HTATIP2; IRF6; CTBP2; RBPMS; CREB3L2; NKX2-1; TOX3; KLF9; WWTR1; IRX5; ID4; ST18; DACH1; KDM5D; TXNIP; TSC22D1
Down-regulation 21 CBFB; IRF4; BRD4; THAP11; MDM2; CENPF; POU2AF1; ZFP36L1; ZNF32; ZNF226; LEF1; VDR; KAT2B; TRIB3; PAX5; FOXO1; MAFB; TFAP2C; TWIST1; EGR1; TRPS1