Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08862 Alpelisib GSE70138 HA1E Human 24h 10uM EID0001
Types Number Response transcription factors
Up-regulation 19 ARID5B; MYC; TSC22D3; MNAT1; CALCOCO1; HMGA2; HOXB6; HDGF; SMAD6; ARNT2; DEK; CITED2; HMGN3; HMGB3; ERBB4; PAWR; MEIS2; FOXG1; TOX3
Down-regulation 21 PAX8; AFF1; LEF1; SOX10; TRIM29; IRF4; NFE2; SSX1; YWHAB; MLXIP; WWC1; EGR1; EGR2; ZFP36L2; NFAT5; NKX3-1; CREB3L2; ZBTB20; BHLHE41; ZNF652; AEBP1