Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08860 Nvp-bez235 GSE70138 HA1E Human 24h 0.12uM EID0001
Types Number Response transcription factors
Up-regulation 128 TCEA2; LZTR1; EZH1; MYC; TGFB1I1; MED15; NR1H2; ZNF282; PPARD; PSMD9; KAT5; EZH2; TTF2; FOSL1; CAMTA2; USF2; NR1I3; MZF1; HDAC6; CBX7; ADRB2; SSBP3; ZMIZ2; TCF25; NR2C1; ELF2; TBX21; ZNF22; BPTF; MED24; ZNF629; ZNF146; KMT2B; ZNF688; HIVEP1; NCOR2; HDAC5; MTA1; ZNF212; FOXN3; CALCOCO1; THRA; DBP; MEOX2; ZNF571; HMGA1; CDK7; ZNF354A; THAP10; ZKSCAN8; ZNF544; HMGA2; ING4; TGIF1; RORA; HBP1; PNRC1; HDAC4; HDAC9; YBX3; NEUROD1; RELA; MNT; ZNF141; ZNF573; FOXG1; FLI1; AR; MAFF; TRIM28; SIX6; TRIP6; KAT7; RBL2; RFX7; SND1; TOPORS; PPP1R13L; KLF11; ZNF266; INSM1; SKI; DEK; AES; GTF2IRD1; VPS72; KDM5D; ZNF83; HMGB3; IRF8; BCL6; ZIC3; PHF20; KLF13; COPS2; ATF4; HOXA5; TCF12; DEAF1; ZNF532; PCGF2; APEX1; ARID1A; TSC22D1; FOXD1; PBX1; PBXIP1; KLF10; ZNF264; JUNB; PDLIM1; MEIS1; ZIC1; KLF2; PSIP1; ST18; PAX6; MAFB; HOXC10; HOXB2; ELK3; KLF6; MNDA; MAF; SOX11; HMG20B; MEIS2; ABL1
Down-regulation 51 MYCBP; XBP1; TBPL1; PAX8; TFDP1; SFPQ; CCNC; YWHAB; DMTF1; WWC1; PKNOX2; ELF5; COPS5; MTF2; GATAD2A; CHD7; XRCC6; PSMC3; RYBP; PITX2; HSBP1; LEF1; HMGN3; ENO1; SOX10; TBL1XR1; ATF3; NFATC3; RFX5; TFDP2; SP140L; TSC22D2; BAZ1A; SIM2; PTTG1; CREB3L2; GATA6; CREB1; RUNX1; STAT3; MAGED1; IRX5; ZMYND8; BHLHE41; MNAT1; BBX; EHF; EGR1; ZHX2; PIR; TOX3