Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID08859	Nvp-bez235	GSE70138	HA1E	Human	24h	0.37uM	EID0001

Response Information :

Types	Number	Response transcription factors
Up-regulation	85	TCEA2; USF2; PPARG; EZH1; ATF4; HDAC5; TCF25; ARID4A; BTF3; HOXB7; ZNF211; HBP1; MAFF; TTF1; MED13; PHF1; CDK7; MNT; HMGA2; BTG1; ING4; DLX2; DDX5; UBE2B; KMT2A; HDAC7; PRMT2; TGIF1; SOX4; TDRD3; CBX7; LHX2; TGFB1I1; ZNF32; BRD8; SMARCC2; FOXN3; ZNF302; DDIT3; SUPT3H; MTA1; NPM1; FOXD1; ZNF184; HMGA1; ING3; BRCA1; HMGB3; PHIP; GTF3A; ZNF83; KLF2; CNBP; TCF7; KLF11; INSM1; APEX1; HEY1; HTATIP2; TDP2; YBX3; GTF2IRD1; HOXA5; NR2F2; CEBPB; KLF6; KLF13; INSR; FOXG1; NR1D2; AHR; HOXC6; MXI1; TOB1; CREBL2; RUNX3; REPIN1; FLNA; NPAS2; KDM5D; KLF10; NR4A2; ASCL1; FOXO4; HMG20B
Down-regulation	53	MYCBP; PAX8; NFKBIA; XBP1; RUVBL1; MED21; CALR; SUB1; SFPQ; MAGED1; NFIL3; KLF1; AR; WDR77; SMARCA5; CREB3L2; WWC1; CREB5; SIAH2; PLAGL2; MSX1; BHLHE40; TRIM16; ISL1; RLF; C1QBP; PITX1; CTNNB1; NFE2; ESR1; PTTG1; ASXL1; PITX2; HIPK1; ZBED2; SMARCA1; REL; TCF21; MYBL1; SMAD1; PEG3; HMGN3; ENO1; FOXF1; VDR; LEF1; HLF; PLAGL1; PTRF; TGFB1; ABL1; POU2AF1; WT1