Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08858 Nvp-bez235 GSE70138 HA1E Human 24h 1.11uM EID0001
Types Number Response transcription factors
Up-regulation 116 TCFL5; TCEA2; PPARD; SSBP2; HDAC5; EZH1; HMGA1; ZNF282; LDB1; PSMD9; KAT5; FOSL1; MYC; MTF2; USP21; RING1; HDAC6; ING4; ZNF408; FOXD1; CALCOCO1; USF2; TCF25; CAMTA2; MTA1; MED15; GFI1B; NR3C1; HMGA2; HDAC9; HBP1; NR2E1; ZNF33B; DDIT3; ZNF573; ZNF43; ZNF212; MZF1; PCGF1; ZNF23; DBP; EHMT2; TFEB; HDAC7; KLF13; SSBP3; FOXG1; GTF2IRD1; PRPF6; ZNF219; POLR3C; MXI1; PHF20; YBX3; ATF4; TDRD3; MEOX2; TRIP6; CDK7; ZNF12; FOXN3; ZNF117; CBX7; NCOR2; ZNF83; VPS72; PMS1; SND1; ZZZ3; SOX9; SLC2A4RG; TRIM28; BAZ2B; ZNF302; ING3; IRF8; ZNF232; TCF12; ZNF551; PBXIP1; DEAF1; HLX; SOX11; SMAD1; PLAG1; ZNF264; FOXF2; ZBED1; CEBPB; COPS2; ZNF532; ZNF91; ZNF22; TSC22D1; HOXA5; INSM1; HEY1; APEX1; BTG1; ARID1A; MEIS2; TRPS1; PAX6; NR4A2; IFI16; ZEB1; TBL1X; OSR2; FOXO4; ZNF423; ID3; ARNT2; POU2AF1; MAF; HMG20B; ABL1
Down-regulation 46 MYCBP; XBP1; HIF1A; TBPL1; PAX8; SFPQ; NFKBIA; PPRC1; GATAD2A; TRIM16; ESR1; TSC22D2; CCNC; SUB1; HIPK1; DDX5; PRRX1; EHF; WWC1; WDR77; TEAD1; TMF1; E2F3; YWHAB; ZMIZ1; BAZ1A; CTR9; ETS1; BIRC2; RFX5; SOX10; MYCN; PTRF; HOXC6; ZBTB18; MYB; LMCD1; PTTG1; PEG3; RUNX1; FOSL2; GATA6; NFATC3; WT1; MNAT1; SNAI2