Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08816 Pf-477736 GSE70138 HA1E Human 24h 3.33uM EID0001
Types Number Response transcription factors
Up-regulation 66 E2F2; NFKBIA; RELB; FOSB; NR4A2; SMARCD2; FOS; HDAC6; TOB1; BRD2; ATF3; TAF12; TSC22D3; JUNB; DDIT3; ZNF529; CEBPB; BTG1; ATF5; ZFPM2; YBX3; ZNF331; NFIL3; ZBTB43; THAP10; JUP; ID2; CITED2; FOXM1; HMGB3; BIRC2; ATF4; BRD4; ZNF302; OSR2; EGR1; PCGF2; SPIB; NKX3-1; ZNF83; RUNX3; KLF4; CEBPG; CUX2; RNF138; TGFB1; KLF5; TOX; HEY1; TAL1; ISL1; DLX5; TRIM22; HMGB2; HES1; PEG3; HOXD1; ID3; PBX1; HHEX; ID1; ARNT2; TSC22D1; DACH1; FOXO4; HMG20B
Down-regulation 50 NRIP1; ERBB2; PAX8; MYC; ARID5B; NCOA4; ZMIZ1; NPAT; ATF7IP; TBL1XR1; HOXA10; FOXO3; TFEB; NPM1; SMAD7; RBM14; KLF7; RREB1; CALR; ZBTB1; CUX1; TSC22D2; ASXL1; CHD7; PITX2; RNF111; ZHX2; ENO1; YWHAB; MAGED1; MYCN; WWC1; LEF1; PDLIM1; CREB1; ZEB2; SOX10; HOXB7; CTNNB1; ELK3; ZBTB38; ZBED2; TFAP2C; LMCD1; MYRF; ZNF652; TOX3; SSBP2; NR3C1; SATB1