Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08815 Pf-477736 GSE70138 HA1E Human 24h 10uM EID0001
Types Number Response transcription factors
Up-regulation 63 SUV39H1; NFKBIA; RELB; NFKB2; EGR1; FOSB; NR4A2; ATF3; ADRB2; NR4A1; EYA2; SAP18; EGR3; BRCA1; JUNB; FOS; PSMC3IP; ATF5; CEBPD; TP63; NAB1; KLF5; TRIM29; REL; DDIT3; RBBP7; ITGB3BP; KLF11; HDAC9; MEIS1; IRF1; ZFPM2; JUP; SMAD3; GLI3; ZNF331; E2F8; TOX; SPIB; BIRC2; NR4A3; MITF; RUNX3; CREM; CEBPB; IRF6; SREBF1; TOB1; CITED2; RFX5; TSC22D1; NKX3-1; NFIB; BCL6; EGR2; ELF3; KDM5D; MEIS2; MAFB; MNDA; ESR1; TRIM22; NFATC3
Down-regulation 57 RUVBL1; GABPB1; MYC; ARID5B; ARID4B; XBP1; HOXA10; MTDH; ATF6; MBD2; FOXO3; ENO1; IRF4; ORC2; KDM5B; HEY1; TBL1XR1; CREB1; DLX2; MAGED1; PITX2; IKBKAP; TULP4; RAN; HOXB6; RARA; HOXC6; YWHAB; ZBTB38; SMAD7; TCF4; SP3; ZNF512B; ZNF281; ID4; THAP11; HIPK3; SMAD1; IL16; ASCL1; HMGB2; HOXC10; LMCD1; PAWR; ZHX2; TLE4; HIRA; ELK3; MYRF; KLF9; PTRF; SOX9; GATA6; SNAI2; LEF1; PPARG; NR3C1