Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08808 Roscovitine GSE70138 HA1E Human 24h 0.04uM EID0001
Types Number Response transcription factors
Up-regulation 46 IKZF1; CEBPD; FOXJ3; HES1; TOX; RUNX3; PRKDC; FOXA2; TBX21; ZBTB16; SOX4; CEBPA; GATA2; NAB2; BHLHE40; HLF; MYT1L; TRIM24; KLF13; DAXX; DBP; CALR; JUP; FOXO1; SMAD7; TGFB1; VPS72; CBX6; TAL1; RUNX1; ENO1; SMAD1; PDLIM1; TOB1; PITX1; ETS2; CEBPB; JUNB; RBPMS; RXRA; HOXB2; HEY1; PEG3; OSR2; TSC22D1; HMG20B
Down-regulation 56 FOSB; TFDP1; PSMC3IP; CCNH; ZFX; TEAD1; CREB5; ENY2; MED21; DLX2; ZNF43; MEOX1; ZNF222; ZNF32; TMF1; PFDN5; RBM39; ABL1; BBX; ATF3; RBPJ; GTF3A; ZNF721; RRN3; KLF2; MAX; ZNF93; CEBPG; KLF4; EYA1; PHIP; ZNF423; HTATIP2; WWP1; SP100; PITX2; BASP1; SP110; CARHSP1; ZBTB20; RFX5; JAK2; TCF7; SOX10; SIX2; HMGA1; PBX3; ZBTB18; PTTG1; LITAF; NR2F2; ZBED2; ZIC1; SOX11; FOXC1; TXNIP