Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08803 Roscovitine GSE70138 HA1E Human 24h 10uM EID0001
Types Number Response transcription factors
Up-regulation 8 TCEA2; TFAP2A; SMAD3; TOB1; HLTF; SIX2; RUNX3; ZNF331
Down-regulation 49 NFKBIA; RELB; GABPB1; TLE4; ID4; LMCD1; IRF1; CREB1; PNRC1; BACH1; BTG1; C1QBP; IRF2; E2F5; TCF4; CALR; RYBP; HSBP1; CTNNB1; PBXIP1; THAP11; JUNB; KLF2; NCOA1; MYCL; ZEB2; ARID1A; EGR1; MYB; GATA6; ZHX2; ZFP36L2; SIAH2; FOXO1; NR2F2; MAFB; AEBP1; CRYM; CEBPB; SMAD1; ETS2; TBL1X; ELF3; ASCL1; ZBTB18; PITX1; CITED2; MAF; TOX3