Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08801 Torin-2 GSE70138 HA1E Human 24h 0.12uM EID0001
Types Number Response transcription factors
Up-regulation 69 TCEA2; HDAC6; MYC; HMGA2; EZH1; ING4; FOSL1; WHSC1; BTF3; MAFF; MXD3; ZNF211; CBFA2T2; SCAND1; COPS5; ZNF93; TCF25; BANP; BRD8; EDF1; HMGB3; PRPF6; NCOA6; UBE2B; CALCOCO1; HOXA5; CBX7; MTA1; RNF14; YBX3; TCEA1; TERF1; ETV5; MXI1; KLF3; ZNF32; ZNF552; PHIP; CREBL2; ELF3; TGIF1; TGFB1I1; BATF; TCEB2; NR1H3; ATF4; HOXD1; TLE2; KLF2; ZNF83; STAT4; TRIP6; INSM1; FOXD1; MYRF; KDM5D; FOXF2; SOX9; NANOG; FOXG1; CEBPB; ZNF91; FLNA; BHLHE41; ATF3; NFATC3; FOXO4; ABL1; HMG20B
Down-regulation 42 MYCBP; GTF2A2; PAX8; XBP1; HIPK1; BLZF1; C1D; SFPQ; TMF1; ESRRG; TCF21; RNF6; NFIL3; BHLHE40; AFF1; CHD8; RNF111; CERS6; TRIM22; PITX2; BAZ1A; MAGED1; STAT1; TRPS1; TRIM32; YAP1; ELF1; PAX5; RUNX1; RYBP; SIAH2; RFX5; SALL1; NFE2; LEF1; TLE4; CREB3L2; STAT3; SMARCA1; TRIM29; MNAT1; KLF10