Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08800 Torin-2 GSE70138 HA1E Human 24h 0.37uM EID0001
Types Number Response transcription factors
Up-regulation 115 HDAC6; TCEA2; EZH1; FOSL1; KMT2A; ZNF573; BRD2; HDAC5; DDIT3; HMGA2; E2F2; ING3; MNT; ZXDC; KDM5D; TTF1; ATF4; MED1; EP400; BTG1; CXXC1; TDRD3; ZNF544; MLXIPL; BRD8; PAXBP1; TGIF1; ZNF211; ZNF23; ZNF83; ZNF329; HBP1; ZNF3; CIZ1; TAF12; NR4A2; ZNF84; HMGA1; TOB1; MAFB; KLF6; HOXB5; UBE2B; ZNF430; AATF; ZNF33B; KLF13; ZNF195; MAFF; CHD4; SUPT3H; HOXC4; ZNF302; ZNF354A; MTA1; TERF1; YBX3; CEBPZ; HOXB7; ZNF43; ZNF266; SAP18; KLF11; ZNF224; KAT7; NFATC1; TAF10; BANP; TCEA1; HDAC9; EDF1; DEK; ZBED1; BRD4; YEATS4; NR2C1; SMARCC2; HOXA5; ZNF93; WHSC1; ZNF331; SCAND1; ZNF551; INSR; ZNF415; NR1D2; ZNF232; ZNF432; KLF5; HOXB2; GTF2IRD1; BCLAF1; FLNA; ARNTL; CEBPB; APEX1; RUNX3; INSM1; YBX1; ZNF91; PAX6; HMGB2; HOXD1; KLF10; ZNF423; HOXC6; AEBP1; ID3; FOXO4; PBX3; NFATC3; CITED2; ID1; BHLHE41; HMG20B
Down-regulation 49 NFKBIA; ECD; MYCBP; XBP1; PAX8; NCOA4; TRIM16; GTF2A2; GATA4; SUB1; MKL2; CALR; TLE4; PSMC3; CCNC; DLX2; MAGED1; WDR77; ENO1; SIAH2; IRF2; MYBL1; STAT1; BNC2; HLF; ZSCAN31; TFAP2C; RUNX1; PITX2; TBL1XR1; ZNF512B; GATA6; CBFA2T3; WWC1; HMGN3; ZEB1; ZHX2; HIPK3; ZBED2; HEY1; EMX2; BMI1; LEF1; TBX3; RBPMS; MYRF; WT1; TRIM22; MECOM