Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08799 Torin-2 GSE70138 HA1E Human 24h 1.11uM EID0001
Types Number Response transcription factors
Up-regulation 90 DDIT3; HDAC6; PSMD9; PHF1; TCEA2; DMTF1; TCF25; LDB1; EZH1; ATF4; LZTR1; GTF2F1; ZMIZ2; PSPC1; HINFP; CEBPB; ZNF83; CDK7; ERCC3; BRD8; ZNF211; TDRD3; BRD2; HMGA1; HDAC5; PAXBP1; PSMC3IP; ZNF692; HTATIP2; THAP10; HMGA2; CXXC1; ZNF354A; ZNF32; ZNF573; CALCOCO1; SIRT7; ING4; ZNF266; HBP1; BANP; PHIP; MZF1; ZNF302; GON4L; SAFB2; ING3; BRCA1; UBE2B; TAF10; SOX4; ETV4; ZBTB48; NR2C1; PMS1; DEK; ZNF112; TOB1; MTA1; ZNF432; CITED2; SMARCC2; KLF5; E2F8; TRIB3; MED23; KLF11; SPIB; APEX1; NR1H3; YBX3; TDP2; BCL11A; NR4A2; HOXC6; TRIP6; ST18; FOXO4; BTG1; NPAS2; MAFB; ZNF91; IRF8; KDM5D; TRPS1; ZFP36L1; NR2F2; INSM1; HMG20B; TWIST1
Down-regulation 45 NFKBIA; MYCBP; ERBB2; PAX8; ENO1; GTF2A2; MYCN; BHLHE40; XBP1; ZMIZ1; TCF4; HNRNPD; CALR; PSMC3; WWC1; SMARCA5; TRIM16; SUB1; MKL2; NFKB1; TFDP2; CREB3L2; ID4; TBL1XR1; PTRF; IRF4; RBBP7; ID3; ELK3; RUNX1; PIR; SERTAD2; LITAF; ETS2; ZBED2; HEY1; FOXF1; ID1; HIPK3; MNAT1; ZFP36L2; SMAD1; TFEC; TXNIP; SATB1