Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08798 Torin-2 GSE70138 HA1E Human 24h 3.33uM EID0001
Types Number Response transcription factors
Up-regulation 121 ZNF274; PAXBP1; DDIT3; HBP1; DMTF1; HINFP; LDB1; PCGF2; EZH1; PSPC1; TBX21; ZNF84; CAMTA2; HDAC5; BRD2; RXRB; EZH2; ATF4; ZNF23; PMS1; BTG1; MED1; BANP; ZNF573; NFX1; USP21; TCF25; ZNF419; ZNF266; PRDM4; ZNF45; TSC22D3; ZNF606; ZNF692; ING4; KAT2A; ZNF500; ZNF3; PSMC3IP; ZNF140; BTF3; CXXC1; ZNF532; RNF10; TOB1; ARNTL; ING3; HMGA2; ZZZ3; PRDM2; ZBTB48; SOX4; BRD8; SUPT4H1; RCOR3; ZNF536; ZNF83; ZNF544; ZNF324; CBFA2T2; SPIB; ZNF302; RBM39; UBE2B; HTATIP2; TRIB3; MZF1; IRF7; HMGB3; KLF11; FUBP1; ZNF329; ZNF232; NR1H3; THAP10; STAT4; TDP2; ZNF184; DEK; ZNF32; TERF2; TGIF1; HDAC9; PNRC1; STAT1; CEBPB; MAFB; FOXD1; DBP; CBX7; TAF1D; ZNF432; SP110; PAX5; SREBF1; SP100; ZNF331; NR4A2; INSM1; LPIN2; HOXD1; KDM5D; KLF5; ZFPM2; CITED2; TWIST1; FOXO1; APEX1; TBX3; HMGA1; IRF8; FOXO4; ARNT2; ZBTB16; IFI16; FOXG1; HMG20B; MAF; SOX11; HES1; POU2AF1
Down-regulation 72 NFKBIA; MYCBP; PAX8; MTA1; PARP1; MED21; GTF2A2; RUVBL1; PSMC3; CCNA2; ID4; SFPQ; MYCN; SMARCA5; ENO1; WDR77; XBP1; MAGED1; CSDC2; WWC1; PITX2; TEAD1; LEF1; TRIM29; SERTAD2; RBM14; HIPK1; ZMIZ1; CUX1; GATA4; GATAD2A; ZNF165; HDAC1; TFDP2; BHLHE40; CALR; TEAD4; PDLIM1; TAF9B; RERE; UBE2L3; SUB1; EHF; ANKRD1; YAP1; HIPK3; PTRF; WT1; CREB3L1; MED6; SMAD1; NFE2L3; RUNX1; MAX; CITED1; NFE2; CTNNB1; GATA6; REL; NFATC3; HOXC10; ELF5; DNAJC1; MNAT1; PLAGL1; ZEB1; EMX2; SOX9; PEG3; ELK3; SSBP2; ID3