Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08797 Torin-2 GSE70138 HA1E Human 24h 10uM EID0001
Types Number Response transcription factors
Up-regulation 136 DDIT3; HDAC6; LDB1; TCEA2; EZH1; DMTF1; PSMD9; HINFP; TSC22D3; PHF1; PMS1; STAT1; CBFA2T2; PAXBP1; HMGA1; ZXDC; MMS19; CXXC1; SNAPC4; RXRB; CDK9; BRD8; BRD3; ATF4; LZTR1; IRF9; SETDB1; SOX4; NCOA6; ZNF211; IRF7; BRPF1; RNF10; ZNF202; KMT2B; BLM; ZMIZ2; HDAC5; SIRT7; MNT; UIMC1; TBX21; ZNF266; WHSC1; ZNF23; MZF1; EZH2; BRD2; EHMT2; ZBTB48; HTATIP2; ZNF117; BANP; KLF13; NR2C1; PSPC1; GTF2IRD1; ZNF573; ZNF335; CEBPB; ZBTB43; RBM39; TRIP4; KDM5D; CALCOCO1; USP21; HDAC9; CAMTA2; HBP1; SSBP3; MXI1; BTG1; ZNF133; FUBP1; ZNF692; ING4; ZNF544; ZNF354A; SP100; TCF25; ZNF443; MTA1; PHIP; GON4L; CHD3; YBX3; TTF1; ING3; TGIF1; SUPT3H; KLF5; BCL11A; ZNF32; SP110; EDF1; HOXA5; ZNF394; TULP4; ZNF302; RAD21; MED1; CBX4; TRIB3; ZNF93; TDP2; CENPF; TADA3; PNRC1; KLF11; TOB1; SMARCC2; MAFF; NR1H3; PHF20; ZNF83; FOXF2; BRD4; FOXO4; ZKSCAN1; LPIN2; HOXD1; STAT4; TERF2; HDAC4; INSM1; MAFB; NPAS2; NR4A2; TGFB1; APEX1; KLF6; ZNF91; SATB1; HES1; HMG20B; TSC22D1
Down-regulation 77 MYCBP; NFKBIA; PAX8; GTF2A2; PARP1; GABPB1; DR1; TCF4; TSC22D2; SUB1; LITAF; ATF6; ID4; ARID5B; CBFB; MEOX1; TBL1XR1; YAP1; GLI2; MED21; IRF2; PEX2; SMARCA5; IRF4; MKL2; CREB5; MSX1; WDR77; REL; NCOA4; MAGED1; BNC2; WWC1; TEAD1; VDR; TRIM16; CREB3L2; PGR; MED6; ZNF552; RBPMS; HIPK1; EHF; WWP1; LEF1; MITF; SMAD1; TRIM29; SALL1; EGR2; KLF4; TCF7L1; PTRF; ZBTB38; EGR1; ID3; FOSL2; PEG3; ENO1; ELK3; ZNF165; TFAP2C; FLI1; TFEC; EMX2; SIAH2; HIPK3; ZBED2; GATA6; PBX1; MNAT1; ESR1; ZNF652; TLE4; PLAGL1; WT1; MECOM