Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08794 Pelitinib GSE70138 HA1E Human 24h 0.37uM EID0001
Types Number Response transcription factors
Up-regulation 53 FOXO4; TSC22D3; PPARGC1A; DDIT3; ATF4; TRIB3; CBX5; EZH1; HDAC7; XBP1; AES; TGIF1; TCF15; HMGB3; TOB1; HIVEP2; KLF9; MYCN; BCL11A; TULP4; PNRC1; MEF2D; HMGA1; KLF5; MED13; YBX3; JUP; ZNF711; SATB1; ID1; NR1D2; EMX2; FOXC1; TWIST1; BTG1; BBX; LITAF; TRIM29; TXNIP; EHF; ETS2; SIX2; CTBP2; CEBPB; SMARCA1; SOX9; TRPS1; TOX3; ZNF652; PITX1; CITED2; DACH1; TSC22D1
Down-regulation 34 PAX8; EGR2; MSX1; PRRX1; SMAD3; ZNF654; TAL1; PBX3; ZNF226; EGR3; KLF11; ZNF217; ZNF32; CERS4; E2F3; TRIM32; FOSL2; BAZ1A; SP140L; NFIB; RORA; MYRF; VDR; JUND; WWTR1; TLE4; TBX3; IFI16; ELK3; GATA6; MAFB; ZFP36L1; PEG3; WT1