Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08792 Pelitinib GSE70138 HA1E Human 24h 3.33uM EID0001
Types Number Response transcription factors
Up-regulation 70 E2F2; RBBP4; CEBPD; TCEA2; PPARGC1A; NFATC1; ADRB2; STAT2; MYCN; MLLT10; CBX5; NFAT5; HOXB5; HMGB3; PPARG; HDAC6; SAP18; TGIF1; SPIB; LYL1; ERG; PBRM1; ADNP; JUP; PROX1; RBBP5; STAT1; HTATIP2; ARRB1; TFEB; HR; ZNF665; NR3C2; HIPK3; KLF5; TRIM16; EPAS1; ID2; FOXC1; ZNF24; BTG1; ZEB2; IRF9; TFCP2L1; NR1H3; ZBED1; KLF6; PIR; ATF4; LPIN2; TRIM22; ETS2; HMGB1; PAX6; NR1D2; IRF7; HEY2; STAT3; ID1; ISL1; TXNIP; TBX3; INSM1; ID3; TOX3; SOX9; KLF9; TFEC; TSC22D1; NFATC3
Down-regulation 50 ERBB2; ID4; DLX2; TEAD4; ZNF354A; JUN; HIPK1; WWC1; PEX2; TFAP2C; NR4A1; CDK7; DMTF1; PITX2; ZBED2; BATF3; STAT6; SP3; ZNF593; YEATS4; JUND; CRY1; HOXB2; TULP3; CD3D; BNC2; TRIM32; ZNF281; ZNF12; SUB1; ZNF232; IFI16; BRD4; RUNX1; ATF3; ERBB4; VDR; MYRF; ESR1; ELF3; ARNT2; RUNX3; MEIS1; LMCD1; POU2AF1; WT1; ZMYND8; LEF1; HES1; CITED2