Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08788 Azd-6482 GSE70138 HA1E Human 24h 0.37uM EID0001
Types Number Response transcription factors
Up-regulation 40 HES1; HOXB5; TCF4; MNAT1; ETV5; HMGA1; HMGB3; HOXB2; MAFF; TRIP6; TOX; HOXB6; MAFB; KLF5; EYA2; SIX1; SMARCA2; TGIF1; CREBL2; ZNF415; ESR1; NFIB; TCF7L1; IFI16; TCF12; MNDA; ZBED2; DAXX; PBX3; PBX1; SALL2; SOX17; DACH1; ELK3; MECOM; TRPS1; ID3; NR4A2; BHLHE41; EMX2
Down-regulation 13 NRIP1; BATF3; IRF1; IKBKAP; CREB1; KLF2; WWC1; LEF1; STAT4; MYRF; CTNNB1; ZFP36L2; DNMT3B