Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08776 Azd-8330 GSE70138 HA1E Human 24h 0.37uM EID0001
Types Number Response transcription factors
Up-regulation 55 STAT1; IRF9; NFKBIA; ARID5B; PAX8; RELB; BATF; HDAC6; ENY2; SP110; KLF9; PRRX1; BACH1; KLF7; ZEB2; KAT2B; FLNA; PQBP1; MAX; IFI16; EMX2; TSC22D3; NFIL3; RBBP7; MITF; SPIB; BAZ1A; IRF4; KLF4; SAP30; KLF11; TFDP2; SP140L; CD3D; ZBTB16; VDR; TGIF1; MXI1; TXNIP; SALL1; PDLIM1; TOX; TAL1; LMCD1; ASCL1; IRF7; SOX10; TRIM22; STAT3; MAFB; HOXC10; ERBB4; ESR1; PIR; NFATC3
Down-regulation 58 FOSL1; TCEA2; RUVBL1; EZH2; MTF2; MED17; MYC; HMGA1; HOXA5; MLLT10; PRDM10; EGR1; CTCF; YBX3; TGFB1; AES; HOXB2; PBX3; FOSB; TRIM28; CTBP1; NR4A2; ILF2; BACH2; HMGB1; ZNF587; SUB1; ZFHX4; SCAND1; C1QBP; PIAS1; TEAD4; ZNF160; TBX3; E2F5; ERG; CITED2; ZNF423; ZNF83; ZNF22; ID1; NR2F2; ZNF721; ISL1; MAGED1; APEX1; FOXD1; KLF2; CREB1; ARID1A; RBPMS; IRX5; SOX11; SMARCD3; HEY1; TSC22D1; ID3; ZBTB18