Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08775 Azd-8330 GSE70138 HA1E Human 24h 1.11uM EID0001
Types Number Response transcription factors
Up-regulation 51 NFKBIA; EGR1; TSC22D3; ARID5B; ATF3; ID4; TBX2; FOSB; TRIM29; BTG1; MITF; ZNF394; TCF4; HTATIP2; NR4A1; WWC1; KLF9; LMCD1; IRF7; PNRC1; HLTF; ZNF652; KLF5; BCL3; IRF9; TP63; ETS2; JUNB; MYCL; HMBOX1; CBFA2T3; LITAF; TGFB1I1; ERG; TOB1; INSM1; FLNA; YWHAB; KLF6; PDLIM1; MEOX2; HEY1; RUNX3; MEIS1; PIR; EGR3; PTRF; MNDA; SNAI2; TOX3; NFATC3
Down-regulation 40 FOSL1; MYBL1; HMGA2; ETV5; WDR77; PCGF2; RERE; MAGED1; ZNF654; ZZZ3; CREB1; HDAC9; PMS1; SP3; HMGA1; RCOR1; PLAG1; ZNF217; FLI1; HMGB2; TERF2; BACH2; ZNF22; POU2AF1; ZNF593; HMGB1; ZFHX4; HIPK3; CUX2; MYB; HLF; PEG3; SAP30; ZNF423; HOXB2; TBL1X; BHLHE41; ZBTB18; SOX9; NR3C1