Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08774 Azd-8330 GSE70138 HA1E Human 24h 3.33uM EID0001
Types Number Response transcription factors
Up-regulation 62 NFKBIA; TSC22D3; GABPB1; ARID5B; NR1H2; STAT1; PPARG; SMAD7; TOB1; TRIM29; NR3C1; HIVEP1; HTATIP2; ATF3; BTG1; IRF9; KLF2; TCF7L2; MED1; LMCD1; TGIF1; TULP4; TGFB1I1; HOXC10; GATA6; HOXC6; CEBPA; NR1H3; SMAD2; JUNB; IRF7; IRF6; KLF9; POU4F1; NR1D2; LPIN2; FOXC1; CUX1; TRIM16; KLF13; ZEB2; MBD2; TOX3; SMARCA1; SATB1; PAX5; SOX10; HLTF; BBX; MAF; ZHX2; SAP30; BHLHE41; LITAF; ZNF331; ID3; SSX1; ZBED2; PAX6; ZNF652; INSM1; SOX9
Down-regulation 58 FOSL1; RUVBL1; SUZ12; TLE1; ZNF43; PRKDC; WDR77; HDAC9; PA2G4; CBX3; ZNF593; PMS1; BCL11B; EGR1; ZNF654; TWIST1; TCEB2; MSX1; ZNF500; ZZZ3; HDAC1; ESR1; ZNF444; ETV5; RORA; SOX17; AR; SALL2; CARHSP1; BNC2; SUMO1; RERE; WT1; HOXB6; ISL1; ZNF217; ZMYND8; NR2F2; CERS4; MYBL1; TGFB1; ZFP36L1; EYA1; BRD4; HOXB2; HMGA1; EGR3; RXRA; LEF1; FOXG1; MAGED1; HMGN3; MAFB; FOSL2; TFAP2C; HHEX; MECOM; NFATC3