Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08773 Azd-8330 GSE70138 HA1E Human 24h 10uM EID0001
Types Number Response transcription factors
Up-regulation 69 NFKBIA; ARID5B; TSC22D3; HES1; SAP30; KLF9; LZTS1; ZNF10; PRRX1; IRF9; AGO2; MYCN; ZNF43; ZNF571; ZNF7; NFIL3; ID4; TRPS1; NPAT; HOXC10; CAMTA1; CEBPB; SMAD6; SMARCA2; MXD4; HSF1; TOX3; PURA; TOX; LMCD1; ZIC1; TAF10; RBBP7; MXI1; MEIS1; JARID2; ZEB2; DLX5; ID3; SMAD7; STAT5A; MYB; TWIST1; HDAC9; ZNF165; NR1H3; TGFB1I1; KLF10; EHF; JUNB; INSM1; ZBTB16; SSX1; STAT3; NFE2L1; SALL2; SNAI2; PDLIM1; GATA6; PEG3; FLNA; MNDA; HEY1; ID1; ASCL1; ERBB4; PITX1; MEIS2; TXNIP
Down-regulation 66 FOSL1; ZNF148; BRD4; UIMC1; TRIM28; TFAM; ZNF211; BRD2; CCNT1; ZZZ3; AR; TDP2; KMT2B; NPM1; HOXB2; ATN1; ING3; ZFP36L1; SP3; EGR1; RBL2; TRRAP; C1QBP; CHD1; CITED1; FOSB; NKX3-1; CHD4; RBPMS; MYRF; MED1; ZNF12; HMGB1; PRKDC; SUB1; CNOT6; ZNF410; ZNF264; ZNF226; HOXA1; CREB1; HLX; CTR9; AES; BAZ2A; ELK3; TFAP2C; TRIP6; BBX; HOXB7; TCF4; KLF4; RYBP; NANOG; ZBTB38; FOXG1; NR0B1; RNF138; ELF3; ESR1; TGFB1; SMAD1; CITED2; CTBP2; TBL1X; AHR