Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID08769 Ldn-193189 GSE70138 HA1E Human 24h 1.11uM EID0001
Types Number Response transcription factors
Up-regulation 60 NFKB2; CEBPD; HMGA2; SSBP2; FOSL1; PAX8; ETV4; ETV1; DDIT3; CCNT1; PA2G4; ZBTB40; MNAT1; JUN; CDK9; CDK8; HMGA1; NFAT5; ETV5; COPS5; EMX2; TBX3; TCEA1; HOXB2; SMAD5; TCF7; IRF8; YBX3; PSPC1; APEX1; PEG3; HDAC4; NR4A2; ZNF83; TCF21; TRIP6; ZNF331; FOXD1; HIC2; HDAC9; TOB1; LEF1; RBPJ; JAK2; SOX9; RBPMS; SALL2; ZNF721; TBL1X; ESR1; KDM5D; SMARCD3; WT1; ZBTB16; ARNT2; FOXF1; FOXG1; MNDA; MAFB; TSC22D1
Down-regulation 53 NFKBIA; MYBL2; BHLHE40; TP53; RELB; LOXL2; ZNF146; NCOR2; IRF1; ARID5B; MED13; HOXA10; HIVEP1; ELF4; HOXA5; BCL3; ID2; SMAD7; KLF7; ZNF430; TADA3; BTG1; ZSCAN31; DLX2; RUNX1; TCF4; SMAD6; ZMIZ1; JUNB; LITAF; ZNF165; RBBP4; TGFB1; KLF10; NFE2L1; ZEB2; LMCD1; FOXO1; ZKSCAN1; EGR1; PDLIM1; PLAGL1; GATA6; STAT3; EGR2; FLNA; ZBTB18; TWIST1; CREB1; ZNF423; ID3; ATF3; ID1